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Gene Expression Data
Assay Details
Assay
Reference: J:221937 Watson JA, et al., Motor and Sensory Deficits in the teetering Mice Result from Mutation of the ESCRT Component HGS. PLoS Genet. 2015 Jun;11(6):e1005290
Assay type: Western blot
MGI Accession ID: MGI:7509984
Gene symbol: Hgs
Gene name: HGF-regulated tyrosine kinase substrate
Antibody: anti-HRS
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Image: 2D HGS ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Genetic BackgroundMutant Allele(s)Sex
E15 wt E15.0 (a) TS23: brain Strong (b) involves: C57BL/6J Not Specified
E15 tn E15.0 (a) TS23: brain Present (c) B6.C3-Hgstn Hgstn/HgstnNot Specified
P0 wt P0 TS27: brain Strong involves: C57BL/6J Not Specified
P0 tn P0 TS27: brain Present (c) B6.C3-Hgstn Hgstn/HgstnNot Specified
P7 wt P7 TS28: brain Present (d) involves: C57BL/6J Not Specified
P7 tn P7 TS28: brain Weak (c) B6.C3-Hgstn Hgstn/HgstnNot Specified
P14 wt P14 TS28: brain Present (d) involves: C57BL/6J Not Specified
P14 tn P14 TS28: brain Weak (c) B6.C3-Hgstn Hgstn/HgstnNot Specified
P21 wt P21 TS28: brain Present (d) involves: C57BL/6J Not Specified
P21 tn P21 TS28: brain Weak (c) B6.C3-Hgstn Hgstn/HgstnNot Specified
P28 wt P28 TS28: brain Present (d) involves: C57BL/6J Not Specified
P28 tn P28 TS28: brain Trace (c) B6.C3-Hgstn Hgstn/HgstnNot Specified
P35 wt P35 TS28: brain Present (d) involves: C57BL/6J Not Specified
P35 tn P35 TS28: brain Trace (c) B6.C3-Hgstn Hgstn/HgstnNot Specified
Notes:
(a) Age of embryo at noon of plug day not specified in reference.
(b) Highest levels of expression during embryonic development.
(c) Expression reduced compared to wild type at all time points examined.
(d) Expression decreases throughout postnatal development.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory