Gene Expression Data
Assay Details
Assay
|
Reference:
|
J:212415
Kinzel B, et al., Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice. Dev Biol. 2014 Jun 15;390(2):181-90
|
Assay type:
|
In situ reporter (knock in)
|
MGI Accession ID:
|
MGI:7509432
|
Gene symbol:
|
Lgr5
|
Gene name:
|
leucine rich repeat containing G protein coupled receptor 5
|
|
Results
|
Specimen
2B:
(close )
Genetic Background:
|
involves: C57BL/6
|
Mutant Allele(s):
|
Lgr5tm1.1(cre/ERT2)Npa/Lgr5+
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formalin
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: intestine |
Present |
Single cells |
2B bottom
,
2B top
|
Expression is in a few cells in the developing intestinal crypt base.
|
Specimen
3A Lgr5:
(close )
Genetic Background:
|
involves: C57BL/6
|
Mutant Allele(s):
|
Lgr5tm1.1(cre/ERT2)Npa/Lgr5+
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formalin
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: intestine |
Present |
Single cells |
3A Lgr5EGFP
|
Expression is in a few stem cells in the developing intestinal crypt base.
|
Specimen
3A Lgr5KO:
(close )
Structure |
Level |
Pattern |
Image |
Note |
TS24: intestine |
Present |
Single cells |
3A Lgr5KO
|
Expression is in a few stem cells in the developing intestinal crypt base.
|
Specimen
3A Lgr4KO;Lgr5:
(close )
Specimen
3A Lgr4/5dKO:
(close )
Specimen
4B:
(close )
Genetic Background:
|
involves: C57BL/6
|
Mutant Allele(s):
|
Lgr5tm1.1(cre/ERT2)Npa/Lgr5+
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formalin
|
Embedding:
|
Paraffin
|
Specimen
4J Lgr5:
(close )
Genetic Background:
|
involves: C57BL/6
|
Mutant Allele(s):
|
Lgr5tm1.1(cre/ERT2)Npa/Lgr5+
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formalin
|
Embedding:
|
Paraffin
|
Specimen
4J Lgr4KO;Lgr5:
(close )
Specimen
4J Lgr5KO:
(close )
Specimen
4J Lgr4/5dKO:
(close )
Specimen
5B:
(close )
Genetic Background:
|
involves: C57BL/6
|
Mutant Allele(s):
|
Lgr5tm1.1(cre/ERT2)Npa/Lgr5+
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formalin
|
Embedding:
|
Paraffin
|
Specimen
5G Lgr5:
(close )
Genetic Background:
|
involves: C57BL/6
|
Mutant Allele(s):
|
Lgr5tm1.1(cre/ERT2)Npa/Lgr5+
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formalin
|
Embedding:
|
Paraffin
|
Specimen
5G Lgr4KO;Lgr5:
(close )
Specimen
5G Lgr5KO:
(close )
Specimen
5G Lgr4/5dKO:
(close )
Specimen
S6A Lgr5:
(close )
Genetic Background:
|
involves: C57BL/6
|
Mutant Allele(s):
|
Lgr5tm1.1(cre/ERT2)Npa/Lgr5+
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formalin
|
Embedding:
|
Paraffin
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS24: dermis |
fibroblast of dermis |
Present |
Regionally restricted |
S6A Lgr5EGFP
|
Expression is in dermal fibroblasts.
|
Specimen
S6A Lgr4KO; Lgr5:
(close )
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS24: dermis |
fibroblast of dermis |
Present |
Regionally restricted |
S6A Lgr4KO;Lgr5EGFP
|
Expression is in dermal fibroblasts.
|
|