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Gene Expression Data
Assay Details
Assay
Reference: J:256987 Shi B, et al., MORC2B is essential for meiotic progression and fertility. PLoS Genet. 2018 Jan;14(1):e1007175
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7509251
Gene symbol: Meiob
Gene name: meiosis specific with OB domains
Antibody: anti-MEIOB (UP2327)
Detection system: Secondary antibody coupled to fluorescein
Assay notes: Two Meiob antibodies were described, but the one used in this assay was not detailed. Anti-MEIOB (UP-GP 99) MGI:7509130 may have been used in this assay.
Results
Specimen 6B MEIOB +/-: postnatal day 18; Morc2btm1Jw/Morc2b+ (more )
Note: Double labeled: green - Meiob; red - Sycp2 (assay MGI:7509245).
Structure Level Pattern Image Note
TS28: spermatocyte Present 6B +/- MEIOB , 6B +/- merged
Specimen 6B MEIOB -/-: postnatal day 18; Morc2btm1Jw/Morc2btm1Jw (more )
Note: Double labeled: green - Meiob; red - Sycp2 (assay MGI:7509245).
Structure Level Pattern Image Note
TS28: spermatocyte Present 6B -/- merged , 6B -/- MEIOB Number of MEIOB-positve foci increased compared to wild type at zygotene- and pachytene-like stages.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory