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Gene Expression Data
Assay Details
Assay
Reference: J:218202 Mellas RE, et al., NFIB Regulates Embryonic Development of Submandibular Glands. J Dent Res. 2015 Feb;94(2):312-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7507487
Gene symbol: Tjp1
Gene name: tight junction protein 1
Antibody: anti-ZO-1
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 4A: embryonic day 16.5 (more )
Note: Double labeled: green - Tjp1; red - Cdh1 (assay MGI:7507488).
Structure Level Pattern Image Note
TS24: submandibular gland epithelium Present Regionally restricted 4B , 4A Expression is apical.
Specimen 4C: embryonic day 16.5; Nfibtm1Rmg/Nfibtm1Rmg (more )
Note: Double labeled: green - Tjp1; red - Cdh1 (assay MGI:7507488).
Structure Level Pattern Image Note
TS24: submandibular gland epithelium Present Regionally restricted 4D , 4C Expression indicated that the cells are in a disorganized arrangement compared to wild-type.
Specimen 4E: embryonic day 18.5 (more )
Note: Double labeled: green - Tjp1; red - Cdh1 (assay MGI:7507488).
Structure Level Pattern Image Note
TS26: submandibular gland epithelium Present Regionally restricted 4F , 4E Expression is apical.
Specimen 4G: embryonic day 18.5; Nfibtm1Rmg/Nfibtm1Rmg (more )
Note: Double labeled: green - Tjp1; red - Cdh1 (assay MGI:7507488).
Structure Level Pattern Image Note
TS26: submandibular gland epithelium Present Regionally restricted 4H , 4G Expression is apical but this mutant lacks lumen formation compared to wild-type.
Specimen S3: embryonic day 18.5 (more )
Note: Double labeled: green - Tjp1; red - Cdh1 (assay MGI:7507488).
Structure Level Pattern Image Note
TS26: submandibular gland epithelium Present Regionally restricted S3 Expression is apical.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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