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Gene Expression Data
Assay Details
Assay
Reference: J:226844 Collin GB, et al., Disruption of murine Adamtsl4 results in zonular fiber detachment from the lens and in retinal pigment epithelium dedifferentiation. Hum Mol Genet. 2015 Dec 15;24(24):6958-74
Assay type: RT-PCR
MGI Accession ID: MGI:7506575
Gene symbol: Rpe65
Gene name: retinal pigment epithelium 65
Probe: Rpe65-pF, Rpe65-pR
Probe preparation: labelled with SYBR green
Assay notes: Quantitative RT-PCR. Relative expression was normalized to Actinb.
Results Image: 7A Rpe65
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified (a) Amount Genetic BackgroundMutant Allele(s)Sex
1 month WT P m 1 TS28: pigmented retinal epithelium Present Not Specified; total RNA C57BL/6 Not Specified
1 month tvrm267 P m 1 TS28: pigmented retinal epithelium Present Not Specified; total RNA C57BL/6J-Adamtsl4tvrm267/Pjn Adamtsl4tvrm267/Adamtsl4tvrm267Not Specified
3 month WT P m 3 TS28: pigmented retinal epithelium Present Not Specified; total RNA C57BL/6 Not Specified
3 month tvrm267 P m 3 TS28: pigmented retinal epithelium Present Not Specified; total RNA C57BL/6J-Adamtsl4tvrm267/Pjn Adamtsl4tvrm267/Adamtsl4tvrm267Not Specified
6 month WT P m 6 TS28: pigmented retinal epithelium Present Not Specified; total RNA C57BL/6 Not Specified
6 month tvrm267 P m 6 TS28: pigmented retinal epithelium Present Not Specified; total RNA C57BL/6J-Adamtsl4tvrm267/Pjn Adamtsl4tvrm267/Adamtsl4tvrm267Not Specified
Notes:
(a) Expression level in mutants did not differ from controls at 1 and 3 months but were reduced by ~20% at 6 months of age.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory