Gene Expression Data
Assay Details
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Assay
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Reference:
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J:226844
Collin GB, et al., Disruption of murine Adamtsl4 results in zonular fiber detachment from the lens and in retinal pigment epithelium dedifferentiation. Hum Mol Genet. 2015 Dec 15;24(24):6958-74
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7506521
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Gene symbol:
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Fbn1
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Gene name:
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fibrillin 1
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Antibody:
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Anti-rF6H
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Detection system:
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Secondary antibody coupled to Alexa Fluor 488
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Results
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Specimen
3B WT:
postnatal month 6
(more  )
Specimen
3B WT:
(close  )
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Genetic Background:
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C57BL/6
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Age:
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postnatal month 6
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: ciliary zonule |
Strong |
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3B WT top
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Microfibrils of the ciliary zonule were strongly labeled. Staining overlapped with the lens capsule in wild type.
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Specimen
3B tvrm267:
(close )
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Genetic Background:
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C57BL/6J-Adamtsl4tvrm267/Pjn
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Mutant Allele(s):
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Adamtsl4tvrm267/Adamtsl4tvrm267
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Age:
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postnatal month 6
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: ciliary zonule |
Strong |
Regionally restricted |
3B tvrm267 top
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Microfibrils of the ciliary zonule were strongly labeled, as in wild type, but were discontinuous from the ciliary body to lens capsule.
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Analysis Tools
