Gene Expression Data
Assay Details
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Assay
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Reference:
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J:127117
Pitteloud N, et al., Loss-of-function mutation in the prokineticin 2 gene causes Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism. Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17447-52
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7488189
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Gene symbol:
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Gnrh1
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Gene name:
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gonadotropin releasing hormone 1
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Antibody:
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Anti-GnRH
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Detection system:
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Secondary antibody coupled to fluorescein
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Results
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Specimen
3b prok2+/+:
postnatal week 12
(more  )
Specimen
3b prok2+/+:
(close  )
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Genetic Background:
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Not Specified
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Age:
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postnatal week 12
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: median eminence |
neuron of the forebrain |
Present |
Regionally restricted |
3b +/+
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Expression was detected in the immunopositive axons in the median eminence.
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Specimen
3b prok2-/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Prok2tm1Qyz/Prok2tm1Qyz
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Age:
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postnatal week 12
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: median eminence |
neuron of the forebrain |
Present |
Regionally restricted |
3b -/-
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Fewer immunopositive axons were detected in the median eminence of the mutant compared with wild type.
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Analysis Tools
