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Gene Expression Data
Assay Details
Assay
Reference: J:140337 Balastik M, et al., Deficiency in ubiquitin ligase TRIM2 causes accumulation of neurofilament light chain and neurodegeneration. Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):12016-21
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7487991
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved caspase-3
Detection system: Secondary antibody
Results
Specimen S4A: postnatal day 30; Trim2Gt(IRESBetageo)11Pgr/Trim2Gt(IRESBetageo)11Pgr (more )
Structure Cell Type Level Pattern Image Note
TS28: cerebellum Purkinje cell Absent S4A No expression in Purkinje cells at 1 month.
Specimen S4B: postnatal day 62; Trim2Gt(IRESBetageo)11Pgr/Trim2Gt(IRESBetageo)11Pgr (more )
Structure Cell Type Level Pattern Image Note
TS28: cerebellum Purkinje cell Present Single cells S4B Expression in several Purkinje cells at 2 months.
Specimen S4C: postnatal day 30; Trim2Gt(IRESBetageo)11Pgr/Trim2Gt(IRESBetageo)11Pgr (more )
Structure Cell Type Level Pattern Image Note
TS28: cerebellum Purkinje cell Absent S4C No expression in Purkinje cells at 1 month.
Specimen S4D: postnatal day 62; Trim2Gt(IRESBetageo)11Pgr/Trim2Gt(IRESBetageo)11Pgr (more )
Structure Cell Type Level Pattern Image Note
TS28: cerebellum Purkinje cell Present Single cells S4D Expression in several Purkinje cells at 2 months.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/24/2026
MGI 6.24 		The Jackson Laboratory