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Gene Expression Data
Assay Details
Assay
Reference: J:140337 Balastik M, et al., Deficiency in ubiquitin ligase TRIM2 causes accumulation of neurofilament light chain and neurodegeneration. Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):12016-21
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7487988
Gene symbol: Nefl
Gene name: neurofilament, light polypeptide
Antibody: NR4
Detection system: Secondary antibody
Results
Specimen 6C: postnatal day 45; Trim2Gt(IRESBetageo)11Pgr/Trim2Gt(IRESBetageo)11Pgr (more )
Structure Level Pattern Image Note
TS28: cerebellum Present Regionally restricted 6C Expression associated with disorganized neurofilaments in dilated axons.
Specimen 6D: postnatal day 45; Trim2Gt(IRESBetageo)11Pgr/Trim2Gt(IRESBetageo)11Pgr (more )
Structure Level Pattern Image Note
TS28: cerebellum Present Regionally restricted 6D Expression associated with disorganized neurofilaments in dilated axons.
Specimen 6E: postnatal day 45 (more )
Structure Level Pattern Image Note
TS28: cerebellum Present Regionally restricted 6E Expression associated with properly oriented parallel neurofilaments in normal axons.
Specimen 6F: postnatal day 45 (more )
Structure Level Pattern Image Note
TS28: cerebellum Present Regionally restricted 6F Expression associated with properly oriented parallel neurofilaments in normal axons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory