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Gene Expression Data
Assay Details
Assay
Reference: J:96092 Laugwitz KL, et al., Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages. Nature. 2005 Feb 10;433(7026):647-53
Assay type: In situ reporter (transgenic)
MGI Accession ID: MGI:7486145
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Reporter: Cre
Antibody: anti-cre
Detection system: Secondary antibody
Results
Specimen 3c top: embryonic day 9.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Isl1tm1(cre/Esr1*)Krc/Isl1+ (more )
Note: Conditional mutant. Tamoxifen (75 ug/g body weight) was administered to pregnant mice at E7.5. Embryos were isolated at E9.5. Double labeled: red - Isl1 reporter; green - Isl1 protein.
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present 3c top row right , 3c top row middle With tamoxifen treatment, Cre is detected in cell nuclei.
Specimen 3d left: embryonic day 12.0; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Isl1tm1(cre/Esr1*)Krc/Isl1+ (more )
Note: Conditional mutant. Tamoxifen (75 ug/g body weight) was administered to pregnant mice at about E10. Embryos were isolated at E12. Double labeled: red - Isl1 reporter; green - Isl1 protein.
Structure Level Pattern Image Note
TS20: heart right ventricle Absent 3d left pane1 1 , 3d left panel 2
TS20: right atrium Absent 3d left pane1 1 , 3d left panel 2
Specimen 3d right: embryonic day 12.0; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Isl1tm1(cre/Esr1*)Krc/Isl1+ (more )
Note: Conditional mutant. Tamoxifen (75 ug/g body weight) was administered to pregnant mice at about E10. Embryos were isolated at E12. Double labeled: red - Isl1 reporter; green - Isl1 protein.
Structure Level Pattern Image Note
TS20: dorsal mesocardium Present 3d right panel 2 , 3d right panel 1
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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