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Gene Expression Data
Assay Details
Assay
Reference: J:238636 Fededa JP, et al., MicroRNA-34/449 controls mitotic spindle orientation during mammalian cortex development. EMBO J. 2016 Nov 15;35(22):2386-2398
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7482542
Gene symbol: Eomes
Gene name: eomesodermin
Antibody: anti-TBR2
Results
Specimen 3G Het: embryonic day 16.0; Mir34atm1.1Aven/Mir34a+, Mirc21tm1.1Aven/Mirc21+, Mirc34tm1.1Cxu/Mirc34+ (more )
Note: Heterozygous littermate control mice were used but the specific genotype for specimen shown was not detailed.
Structure Level Pattern Image Note
TS24: neocortex Present Regionally restricted 3G Het Expression in intermediate progenitors.
Specimen 3G KO: embryonic day 16.0; Mir34atm1.1Aven/Mir34atm1.1Aven, Mirc21tm1.1Aven/Mirc21tm1.1Aven, Mirc34tm1.1Cxu/Mirc34tm1.1Cxu (more )
Note: Double (DKO) and triple (TKO) knockout littermates were grouped in this study. The specific genotype of the specimen shown was not reported. Embryos may or may not have expressed the Mir34a wild type allele.
Structure Level Pattern Image Note
TS24: neocortex Weak Regionally restricted 3G KO Significantly reduced number of expressing cells compared to control.
Specimen EV3C Het: embryonic day 16.0; Mir34atm1.1Aven/Mir34a+, Mirc21tm1.1Aven/Mirc21+, Mirc34tm1.1Cxu/Mirc34+ (more )
Note: Heterozygous littermate control mice were used but the specific genotype for specimen shown was not detailed.
Structure Level Pattern Image Note
TS24: neocortex Present Regionally restricted EV3C TBR2 Het Expression in intermediate progenitors.
Specimen EV3C KO: embryonic day 16.0; Mir34atm1.1Aven/Mir34atm1.1Aven, Mirc21tm1.1Aven/Mirc21tm1.1Aven, Mirc34tm1.1Cxu/Mirc34tm1.1Cxu (more )
Note: Double (DKO) and triple (TKO) knockout littermates were grouped in this study. The specific genotype of the specimen shown was not reported. Embryos may or may not have expressed the Mir34a wild type allele.
Structure Level Pattern Image Note
TS24: neocortex Weak Regionally restricted EV3C TBR2 KO Significantly reduced number of expressing cells compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory