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Gene Expression Data
Assay Details
Assay
Reference: J:238636 Fededa JP, et al., MicroRNA-34/449 controls mitotic spindle orientation during mammalian cortex development. EMBO J. 2016 Nov 15;35(22):2386-2398
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7482538
Gene symbol: Bcl11b
Gene name: B cell leukemia/lymphoma 11B
Antibody: anti-CTIP2
Results
Specimen 3C Het: embryonic day 16.0; Mir34atm1.1Aven/Mir34a+, Mirc21tm1.1Aven/Mirc21+, Mirc34tm1.1Cxu/Mirc34+ (more )
Note: Heterozygous littermate control mice were used but the specific genotype for specimen shown was not detailed.
Structure Cell Type Level Pattern Image Note
TS24: neocortex neuron of the forebrain Present Regionally restricted 3C Het Expression in neurons of layer V.
Specimen 3C KO: embryonic day 16.0; Mir34atm1.1Aven/Mir34atm1.1Aven, Mirc21tm1.1Aven/Mirc21tm1.1Aven, Mirc34tm1.1Cxu/Mirc34tm1.1Cxu (more )
Note: Double (DKO) and triple (TKO) knockout littermates were grouped in this study. The specific genotype of the specimen shown was not reported. Embryos may or may not have expressed the Mir34a wild type allele.
Structure Level Pattern Image Note
TS24: neocortex Weak Regionally restricted 3C KO Significantly reduced number of expressing cells compared to control.
Specimen EV3A CTIP2 Het: embryonic day 16.0; Mir34atm1.1Aven/Mir34a+, Mirc21tm1.1Aven/Mirc21+, Mirc34tm1.1Cxu/Mirc34+ (more )
Note: Heterozygous littermate control mice were used but the specific genotype for specimen shown was not detailed.
Structure Cell Type Level Pattern Image Note
TS24: neocortex neuron of the forebrain Present Regionally restricted EV3A CTIP2 Het Expression in neurons of layer V.
Specimen EV3A CTIP2 KO: embryonic day 16.0; Mir34atm1.1Aven/Mir34atm1.1Aven, Mirc21tm1.1Aven/Mirc21tm1.1Aven, Mirc34tm1.1Cxu/Mirc34tm1.1Cxu (more )
Note: Double (DKO) and triple (TKO) knockout littermates were grouped in this study. The specific genotype of the specimen shown was not reported. Embryos may or may not have expressed the Mir34a wild type allele.
Structure Level Pattern Image Note
TS24: neocortex Weak Regionally restricted EV3A CTIP2 KO Significantly reduced number of expressing cells compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory