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Gene Expression Data
Assay Details
Assay
Reference: J:335425 Derbyshire ML, et al., Loss of Tbx3 in Mouse Eye Causes Retinal Angiogenesis Defects Reminiscent of Human Disease. Invest Ophthalmol Vis Sci. 2023 May 1;64(5):1
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7482278
Gene symbol: Pdgfra
Gene name: platelet derived growth factor receptor, alpha polypeptide
Antibody: anti-CD140a/Pdgfra (APA5)
Detection system: Secondary antibody coupled to Alexa Fluor 647
Results
Specimen 4A': postnatal day 2; Tbx3tm3.1Moon/Tbx3+ (more )
Structure Cell Type Level Pattern Image Note
TS27: retina retinal astrocyte Present 4A'
Specimen 4B': postnatal day 2; Tbx3tm3.1Moon/Tbx3tm3.1Moon, Tg(Dkk3-cre)D9Tfur/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS27: retina retinal astrocyte Weak Regionally restricted 4B' Expression in fewer retinal astrocytes compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory