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Gene Expression Data
Assay Details
Assay
Reference: J:335425 Derbyshire ML, et al., Loss of Tbx3 in Mouse Eye Causes Retinal Angiogenesis Defects Reminiscent of Human Disease. Invest Ophthalmol Vis Sci. 2023 May 1;64(5):1
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7482271
Gene symbol: Pax2
Gene name: paired box 2
Antibody: anti-Pax2 (#901001, #PRB-276P)
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen 1H: embryonic day 13.5; Tbx3tm2.1Moon/Tbx3+ (more )
Note: Double labeled: red - Pax2; green - Tbx3 reporter (assay MGI:7482268).
Structure Level Pattern Image Note
TS21: optic nerve Present Regionally restricted 1H''' , 1H'' Expression in optic nerve head in cells fated toward an astroglial lineage.
Specimen 1I: postnatal day 0; Tbx3tm3.1Moon/Tbx3+ (more )
Structure Level Pattern Image Note
TS27: retina Present 1I
Specimen 1J: postnatal day 0; Tbx3tm2.1Moon/Tbx3+ (more )
Note: Double labeled: red - Pax2; green - Tbx3 reporter (assay MGI:7482268).
Structure Level Pattern Image Note
TS27: retina Present 1J
Specimen 1J' Dorsal: postnatal day 0; Tbx3tm2.1Moon/Tbx3+ (more )
Note: Double labeled: red - Pax2; green - Tbx3 reporter (assay MGI:7482268).
Structure Level Pattern Image Note
TS27: retina Present 1J'
Specimen 1J'' Ventral: postnatal day 0; Tbx3tm2.1Moon/Tbx3+ (more )
Note: Double labeled: red - Pax2; green - Tbx3 reporter (assay MGI:7482268).
Structure Level Pattern Image Note
TS27: retina Present 1J''
Specimen S2A: embryonic day 13.5; Tbx3tm3.1Moon/Tbx3+ (more )
Structure Level Pattern Image Note
TS21: optic nerve Present Regionally restricted S2A , S2A'
Specimen S2B: embryonic day 13.5; Tbx3tm2.1Moon/Tbx3+ (more )
Note: Double labeled: red - Pax2; green - Tbx3 reporter (assay MGI:7482268).
Structure Level Pattern Image Note
TS21: optic nerve Present Regionally restricted S2B , S2B' Expression in optic nerve head.
Specimen S2C: postnatal day 0; Tbx3tm3.1Moon/Tbx3+ (more )
Structure Level Pattern Image Note
TS27: optic disc Present S2C
Specimen S2D: postnatal day 0; Tbx3tm2.1Moon/Tbx3+ (more )
Note: Double labeled: red - Pax2; green - Tbx3 reporter (assay MGI:7482268).
Structure Level Pattern Image Note
TS27: optic disc Present S2D
Specimen 4C: postnatal day 2; Tbx3tm3.1Moon/Tbx3+ (more )
Structure Cell Type Level Pattern Image Note
TS27: retina retinal astrocyte Present 4C , 4C'
Specimen 4D: postnatal day 2; Tbx3tm3.1Moon/Tbx3tm3.1Moon, Tg(Dkk3-cre)D9Tfur/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS27: retina retinal astrocyte Weak 4D' , 4D Expression in fewer retinal astrocytes compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory