Shh RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:335331 Seppala M, et al., Gas1 Regulates Patterning of the Murine and Human Dentitions through Sonic Hedgehog. J Dent Res. 2022 Apr;101(4):473-482
Assay type:	RNA in situ
MGI Accession ID:	MGI:7481954
Gene symbol:	Shh
Gene name:	sonic hedgehog

Results

Specimen S1A: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: upper jaw primordium	Present	Regionally restricted	S1A	Expression in vestigial tooth primordium (R1).
TS20: lower jaw primordium	Present	Regionally restricted	S1A	Expression in vestigial tooth primordium (MS).

Specimen S1B: embryonic day 13.5 (more

)

Structure	Level	Pattern	Image	Note
TS21: lower jaw mesenchyme	Present	Regionally restricted	S1B	Expression in vestigial tooth primordia (R2).
TS21: upper jaw mesenchyme	Present	Regionally restricted	S1B	Expression in vestigial tooth primordia (R2).
TS21: upper jaw molar	Present

Specimen S1C: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: lower jaw molar	Present		S1C
TS22: upper jaw molar	Present		S1C

Specimen S1D: embryonic day 15.5 (more

)

Structure	Level	Pattern	Image	Note
TS23: lower jaw molar	Present		S1D
TS23: upper jaw molar	Present		S1D

Specimen S1E: embryonic day 15.5 (more

)

Structure	Level	Pattern	Image	Note
TS23: lower jaw molar	Present		S1E
TS23: upper jaw molar	Present		S1E

Specimen 3I: embryonic day 13.5 (more

)

Structure	Level	Pattern	Image	Note
TS21: upper jaw mesenchyme	Present	Regionally restricted	3I	Expression in vestigial tooth primordium (R2).

Specimen 3J: embryonic day 13.5; Gas1^tm1Fan/Gas1^tm1Fan (more

)

Structure	Level	Pattern	Image	Note
TS21: upper jaw mesenchyme	Strong	Regionally restricted	3J	Expression sustained and increased in vestigial tooth primordium (R2) compared to wild type.

Specimen 3K: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: upper jaw molar	Present		3K

Specimen 3L: embryonic day 14.5; Gas1^tm1Fan/Gas1^tm1Fan (more

)

Structure	Level	Pattern	Image	Note
TS22: upper jaw mesenchyme	Strong	Regionally restricted	3L	Expression sustained and increased in vestigial tooth primordium (R2) compared to wild type.

Specimen S4A: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: upper jaw primordium	Present		S4A

Specimen S4B: embryonic day 13.5 (more

)

Structure	Level	Pattern	Image	Note
TS21: upper jaw molar	Present		S4B

Specimen S4C: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: upper jaw molar	Present		S4C

Specimen S4D: embryonic day 15.5 (more

)

Structure	Level	Pattern	Image	Note
TS23: upper jaw molar	Present		S4D

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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