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Gene Expression Data
Assay Details
Assay
Reference: J:207609 Hilliard SA, et al., Mdm2 is required for maintenance of the nephrogenic niche. Dev Biol. 2014 Mar 1;387(1):1-14
Assay type: RNA in situ
MGI Accession ID: MGI:7481343
Gene symbol: Lhx1
Gene name: LIM homeobox protein 1
Probe: Lhx1 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 7E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: early nephron Present 7E
Specimen 7F: embryonic day 14.5; Mdm2tm1.2Mep/Mdm2tm1.2Mep, Tg(Six2-GFP/cre)1Amc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: early nephron Present 7F There were far fewer positive nascent nephrons (control kidneys have 3-fold more over the mutant kidneys).
Specimen not shown: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: early nephron Present
Specimen not shown: embryonic day 15.5; Mdm2tm1.2Mep/Mdm2tm1.2Mep, Tg(Six2-GFP/cre)1Amc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: early nephron Present There were far fewer positive nascent nephrons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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