About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:207609 Hilliard SA, et al., Mdm2 is required for maintenance of the nephrogenic niche. Dev Biol. 2014 Mar 1;387(1):1-14
Assay type: RNA in situ
MGI Accession ID: MGI:7481342
Gene symbol: Wnt4
Gene name: wingless-type MMTV integration site family, member 4
Probe: Wnt4 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 7C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: early nephron Present 7C
Specimen 7D: embryonic day 14.5; Mdm2tm1.2Mep/Mdm2tm1.2Mep, Tg(Six2-GFP/cre)1Amc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: early nephron Present 7D There were far fewer positive nascent nephrons (control kidneys have 3-fold more over the mutant kidneys).
Specimen S4E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: early nephron Present S4E
Specimen S4F: embryonic day 13.5; Mdm2tm1.2Mep/Mdm2tm1.2Mep, Tg(Six2-GFP/cre)1Amc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: early nephron Present S4F Similar expression as in the control.
Specimen not shown: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: early nephron Present
Specimen not shown: embryonic day 15.5; Mdm2tm1.2Mep/Mdm2tm1.2Mep, Tg(Six2-GFP/cre)1Amc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: early nephron Present There were far fewer positive nascent nephrons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/28/2024
MGI 6.13 		The Jackson Laboratory