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Gene Expression Data
Assay Details
Assay
Reference: J:97217 Wagner N, et al., A splice variant of the Wilms' tumour suppressor Wt1 is required for normal development of the olfactory system. Development. 2005 Mar;132(6):1327-36
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7481289
Gene symbol: Ascl1
Gene name: achaete-scute family bHLH transcription factor 1
Antibody: Anti-Mash1 (AB5696)
Detection system: Secondary antibody coupled to Cy3
Assay notes: Two antibodies for Ascl1 were listed in the methods MGI:5574500 and MGI:7471200; either could have been used.
Results
Specimen 5A: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: olfactory epithelium Present Regionally restricted 5A Expression was detected in the basal region of the olfactory epithelium.

Specimen 5D: embryonic day 18.5; Wt1tm2Asc/Wt1tm2Asc (more )
Structure Level Pattern Image Note
TS26: olfactory epithelium Present Regionally restricted 5D Expression was detected in the basal region of the olfactory epithelium.

Specimen 5G: embryonic day 18.5; Wt1tm1Asc/Wt1tm1Asc (more )
Structure Level Pattern Image Note
TS26: olfactory epithelium Weak Regionally restricted 5G Immunoreactivity was reduced dramatically in the olfactory epithelium of mouse embryos with lack of the Wt1(+KTS) protein.

Specimen 6Cb: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: olfactory epithelium Present Regionally restricted 6Cb , 6Cc , 6Cd Wt1- and Ascl1- immunoreactivities partially overlapped in the olfactory epithelium.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory