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Gene Expression Data
Assay Details
Assay
Reference: J:218286 Yang X, et al., Matrilin-3 inhibits chondrocyte hypertrophy as a bone morphogenetic protein-2 antagonist. J Biol Chem. 2014 Dec 12;289(50):34768-79
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7470926
Gene symbol: Smad1
Gene name: SMAD family member 1
Antibody: Anti-phospho-Smad1
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 3E WT top: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: epiphyseal plate Present Regionally restricted 3E Matn3+/+ top Expression was detected through the entirety of the growth plate.
TS26: tibia Present Regionally restricted 3E Matn3+/+ top Expression was detected through the entirety of the growth plate.
Specimen 3E WT middle: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: epiphyseal plate Present Regionally restricted 3E Matn3+/+ middle Expression was detected through the entirety of the growth plate.
TS26: tibia Present Regionally restricted 3E Matn3+/+ middle Expression was detected through the entirety of the growth plate.
Specimen 3E WT bottom: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: epiphyseal plate hypertrophic zone Present Regionally restricted 3E Matn3+/+ bottom Expression was detected through the entirety of the growth plate.
TS26: tibia Present Regionally restricted 3E Matn3+/+ bottom Expression was detected through the entirety of the growth plate.
Specimen 3E Matn3-/- top: embryonic day 18.5; Matn3tm1Brd/Matn3tm1Brd (more )
Structure Level Pattern Image Note
TS26: epiphyseal plate Present Regionally restricted 3E Matn3-/- top Expression was detected through the entirety of the growth plate. In the mutant, the expression was upregulated in epiphyseal cartilage.
TS26: tibia Present Regionally restricted 3E Matn3-/- top Expression was detected through the entirety of the growth plate. In the mutant, the expression was upregulated in epiphyseal cartilage.
Specimen 3E Matn3-/- middle: embryonic day 18.5; Matn3tm1Brd/Matn3tm1Brd (more )
Structure Level Pattern Image Note
TS26: epiphyseal plate Present Regionally restricted 3E Matn3-/- middle Expression was detected through the entirety of the growth plate. In the mutant, the expression was upregulated in columnar cartilage.
TS26: tibia Present Regionally restricted 3E Matn3-/- middle Expression was detected through the entirety of the growth plate. In the mutant, the expression was upregulated in columnar cartilage.
Specimen 3E Matn3-/- bottom: embryonic day 18.5; Matn3tm1Brd/Matn3tm1Brd (more )
Structure Level Pattern Image Note
TS26: epiphyseal plate hypertrophic zone Present Regionally restricted 3E Matn3-/- bottom Expression was detected through the entirety of the growth plate. In the mutant, the expression was not upregulated in the hypertrophic cartilage.
TS26: tibia Present Regionally restricted 3E Matn3-/- bottom Expression was detected through the entirety of the growth plate. In the mutant, the expression was not upregulated in the hypertrophic cartilage.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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