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Gene Expression Data
Assay Details
Assay
Reference: J:124279 Zhang B, et al., Mice lacking sister chromatid cohesion protein PDS5B exhibit developmental abnormalities reminiscent of Cornelia de Lange syndrome. Development. 2007 Sep;134(17):3191-201
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7468967
Gene symbol: Gcna
Gene name: germ cell nuclear acidic protein
Antibody: anti-GCNA1
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 5A: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: germ cell of ovary Present 5A
Specimen 5B: postnatal day 0; Pds5btm1Jmi/Pds5btm1Jmi (more )
Structure Level Pattern Image Note
TS27: germ cell of ovary Weak 5B Severely reduced numbers of germ cells compared to wildtype.
Specimen 5C: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: germ cell of testis Present 5C
Specimen 5D: postnatal day 0; Pds5btm1Jmi/Pds5btm1Jmi (more )
Structure Level Pattern Image Note
TS27: germ cell of testis Weak 5D Severely reduced numbers of germ cells compared to wildtype.
Specimen 5E: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: germ cell of testis Present 5E
Specimen 5F: embryonic day 18.5; Pds5btm1Jmi/Pds5btm1Jmi (more )
Structure Level Pattern Image Note
TS26: germ cell of testis Weak 5F 80% reduction in germ cells compared to wildtype.
Specimen S4E: embryonic day 12.5 (more )
Note: Double labeled: red - GCNA; green - BrdU.
Structure Level Pattern Image Note
TS20: germ cell of testis Present S4E
Specimen S4F: embryonic day 12.5; Pds5btm1Jmi/Pds5btm1Jmi (more )
Note: Double labeled: red - GCNA; green - BrdU.
Structure Level Pattern Image Note
TS20: germ cell of testis Weak S4F Decreased numbers of dividing germ cells compared to wildtype.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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