Cdh1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:248183 Mathew S, et al., Talin regulates integrin beta1-dependent and -independent cell functions in ureteric bud development. Development. 2017 Nov 15;144(22):4148-4158
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7468696
Gene symbol:	Cdh1
Gene name:	cadherin 1

Antibody:	clone ECCD-2 (#13-1900)
Detection system:	Secondary antibody coupled to Alexa Fluor 568

Results

3D ©

Specimen 3D: embryonic day 15.5; Itgb1^tm1Ref/Itgb1^tm1Ref (more

)

Structure	Level	Pattern	Image	Note
TS23: collecting duct	Present		3D

3E ©

Specimen 3E: embryonic day 15.5; Itgb1^tm12.1Ref/Itgb1^tm1Ref, Tg(Hoxb7-cre)13Amc/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS23: collecting duct	Present		3E	About 50% fewer ureteric bud tips compared with the wild-type (Fig 3H).

3F ©

Specimen 3F: embryonic day 15.5; Itgb1^tm1Ref/Itgb1^tm1Ref (more

)

Structure	Level	Pattern	Image	Note
TS23: collecting duct	Present		3F

3G ©

Specimen 3G: embryonic day 15.5; Itgb1^tm12.1Ref/Itgb1^tm1Ref, Tg(Hoxb7-cre)13Amc/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS23: collecting duct	Present		3G	Ureteric tips were broader and misshapen compared with wild type.

7F ©

Specimen 7F: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: primitive collecting duct	Present		7F	Ureteric buds had branched several times.

7G ©

Specimen 7G: embryonic day 12.5; Tg(Hoxb7-cre)13Amc/0, Tln1^tm4.1Crit/Tln1^tm4.1Crit, Tln2^tm2Crit/Tln2^tm2Crit (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS20: primitive collecting duct	Present		7G	Ureteric bud was halted at a T-shaped stage.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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