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Gene Expression Data
Assay Details
Assay
Reference: J:260692 Yagi H, et al., Filamin A-interacting protein (FILIP) is a region-specific modulator of myosin 2b and controls spine morphology and NMDA receptor accumulation. Sci Rep. 2014 Sep 15;4:6353
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7468606
Gene symbol: Filip1
Gene name: filamin A interacting protein 1
Reporter: lacZ
Direct Detection
Results
Specimen 1c: postnatal week 12; Filip1tm1Msat/Filip1tm1Msat (more )
Structure Level Pattern Image Note
TS28: anterior olfactory nucleus Present 1c
TS28: olfactory tubercle Present 1c
TS28: piriform cortex Present 1c
Specimen 1d: postnatal week 12; Filip1tm1Msat/Filip1tm1Msat (more )
Structure Level Pattern Image Note
TS28: accumbens nucleus Present 1d
TS28: olfactory tubercle Present 1d
TS28: piriform cortex Present 1d
TS28: frontal cortex Present Regionally restricted 1d Expression was detected in the motor cortex.
TS28: forebrain Present Regionally restricted 1d Expression was detected in ventral forebrain.
Specimen 1e: postnatal week 12; Filip1tm1Msat/Filip1tm1Msat (more )
Structure Level Pattern Image Note
TS28: globus pallidus Present 1e
TS28: olfactory tubercle Present 1e
TS28: piriform cortex Present 1e
TS28: frontal cortex Present Regionally restricted 1e Expression was detected in the motor cortex.
Specimen 1f: postnatal week 12; Filip1tm1Msat/Filip1tm1Msat (more )
Structure Level Pattern Image Note
TS28: arcuate nucleus Present 1f
TS28: piriform cortex Present 1f
TS28: amygdala Present Regionally restricted 1f Expression was in the amygdaloid complex.
Specimen 1g: postnatal week 12; Filip1tm1Msat/Filip1tm1Msat (more )
Structure Level Pattern Image Note
TS28: piriform cortex Present 1g
TS28: visual cortex Present 1g
TS28: amygdala Present Regionally restricted 1g Expression was in the amygdaloid complex.
Specimen 1h: postnatal week 12; Filip1tm1Msat/Filip1tm1Msat (more )
Structure Level Pattern Image Note
TS28: visual cortex Present 1h
TS28: amygdala Present Regionally restricted 1h Expression was in the amygdaloid complex.
Specimen 1i: postnatal week 12; Filip1tm1Msat/Filip1tm1Msat (more )
Structure Level Pattern Image Note
TS28: visual cortex Present 1i
Specimen 8a: postnatal adult; Filip1tm1Msat/Filip1tm1Msat (more )
Structure Level Pattern Image Note
TS28: cortical layer II Present Regionally restricted 8a X-Gal , 8a merged Expression was detected in layers II/III of the visual cortex.
TS28: cortical layer III Present Regionally restricted 8a X-Gal , 8a merged Expression was detected in layers II/III of the visual cortex.
TS28: visual cortex Present Regionally restricted 8a X-Gal , 8a merged Expression was detected in layers II/III of the visual cortex.
Specimen S2a: postnatal week 12; Filip1tm1Msat/Filip1tm1Msat (more )
Structure Level Pattern Image Note
TS28: accumbens nucleus Present S2a
TS28: olfactory tubercle Present S2a
TS28: piriform cortex Present S2a
TS28: forebrain Present Regionally restricted S2a Expression was detected in ventral forebrain.
TS28: frontal cortex Present Regionally restricted S2a Expression was detected in motor cortex.
Specimen S2b: postnatal week 12; Filip1tm1Msat/Filip1tm1Msat (more )
Structure Level Pattern Image Note
TS28: globus pallidus Present S2b
TS28: olfactory tubercle Present S2b
TS28: piriform cortex Present S2b
TS28: frontal cortex Present Regionally restricted S2b Expression was detected in motor cortex.
Specimen S2c: postnatal week 12; Filip1tm1Msat/Filip1tm1Msat (more )
Structure Level Pattern Image Note
TS28: arcuate nucleus Present S2c
TS28: piriform cortex Present S2c
TS28: amygdala Present Regionally restricted S2c Expression was in the amygdaloid complex.
Specimen S2d: postnatal week 12; Filip1tm1Msat/Filip1tm1Msat (more )
Structure Level Pattern Image Note
TS28: piriform cortex Present S2d
TS28: visual cortex Present S2d
TS28: amygdala Present Regionally restricted S2d Expression was in the amygdaloid complex.
Specimen S2e: postnatal day 15; Filip1tm1Msat/Filip1+ (more )
Structure Level Pattern Image Note
TS28: piriform cortex Present S2e
Specimen S2f: postnatal day 15; Filip1tm1Msat/Filip1+ (more )
Structure Level Pattern Image Note
TS28: piriform cortex Present S2f
Specimen S2g top: postnatal; Filip1tm1Msat/Filip1tm1Msat (more )
Note: Double labeled: gray - Filip1 reporter; green - Rbfox3 (assay MGI:7468716).
Structure Cell Type Level Pattern Image Note
TS28: piriform cortex neuron of the forebrain Present Regionally restricted S2g merged top , S2g X-gal top Expression was detected in neurons of the upper layer III of the piriform cortex. Co-localization was noted with Rbfox3 (NeuN).
Specimen S2g middle: postnatal; Filip1tm1Msat/Filip1tm1Msat (more )
Note: Double labeled: gray - Filip1 reporter; red - Map2 (assay MGI:7468721).
Structure Cell Type Level Pattern Image Note
TS28: piriform cortex neuron of the forebrain Present Regionally restricted S2g merged middle , S2g X-gal middle Expression was detected in neurons of the upper layer III of the piriform cortex. Co-localization was noted with Map2.
Specimen S2g bottom: postnatal; Filip1tm1Msat/Filip1tm1Msat (more )
Note: Double labeled: gray - Filip1 reporter; green - Gad1 (assay MGI:7468726).
Structure Cell Type Level Pattern Image Note
TS28: piriform cortex glutamatergic neuron Present Regionally restricted S2g X-gal bottom , S2g merged bottom Expression was detected in glutamatergic neurons of the layer II of the piriform cortex. Co-localization was not seen with Gad1.
TS28: piriform cortex GABAergic neuron Absent S2g merged bottom , S2g X-gal bottom
Specimen S2h Visual cortex: postnatal adult; Filip1tm1Msat/Filip1tm1Msat (more )
Note: Double labeled: orange - Filip1 reporter; green - Pou3f3 (assay MGI:7468732).
Structure Cell Type Level Pattern Image Note
TS28: visual cortex neuron of the forebrain Present Regionally restricted S2h Visual cortex X-Gal-positive cells were also positive for Pou3f3 (Brn1).
Specimen S2h Piriform cortex: postnatal adult; Filip1tm1Msat/Filip1tm1Msat (more )
Note: Double labeled: orange - Filip1 reporter; green - Pou3f3 (assay MGI:7468732).
Structure Cell Type Level Pattern Image Note
TS28: piriform cortex neuron of the forebrain Present Regionally restricted S2h Piriform cortex X-Gal-positive cells were also positive for Pou3f3 (Brn1).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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