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Gene Expression Data
Assay Details
Assay
Reference: J:297164 Nie X, et al., mTOR plays a pivotal role in multiple processes of enamel organ development principally through the mTORC1 pathway and in part via regulating cytoskeleton dynamics. Dev Biol. 2020 Nov 1;467(1-2):77-87
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7467222
Gene symbol: Cdkn1a
Gene name: cyclin dependent kinase inhibitor 1A
Antibody: anti-p21
Detection system: Secondary antibody coupled to Alexa Fluor 546
Results
Specimen 5R: embryonic day 18.5; Mtortm1.2Koz/Mtor+ (more )
Structure Cell Type Level Pattern Image Note
TS26: lower jaw molar enamel organ ameloblast Present 5R
Specimen 5S: embryonic day 18.5; Mtortm1.2Koz/Mtortm1.2Koz, Tg(KRT14-cre)1Amc/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: lower jaw molar enamel organ ameloblast Strong 5S Significantly increased expression compared to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory