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Gene Expression Data
Assay Details
Assay
Reference: J:324720 Zhao Q, et al., Drp1 regulates transcription of ribosomal protein genes in embryonic hearts. J Cell Sci. 2022 Feb 15;135(4):jcs258956
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7467168
Gene symbol: Casp3
Gene name: caspase 3
Results
Specimen 2C Ctrl (upper0: embryonic day 12.5; Dnm1ltm1.1Hise/? (more )
Note: Double labeled: green - Casp3; red - MHC.
Structure Level Pattern Image Note
TS20: heart right ventricle Present 2C Ctrl (upper left merge)
Specimen 2C Mut (upper): embryonic day 12.5; Dnm1ltm1.1Hise/Dnm1ltm1.1Hise, Tg(Mef2c-cre)2Blk/0 (more )
Note: Conditional mutant. Double labeled: green - Casp3; red - MHC.
Structure Level Pattern Image Note
TS20: heart left ventricle Strong 2C Mut (upper right inset) , 2C Mut (upper right merge) Significantly increased apoptosis in right ventricle compared to control.
Specimen 2C Ctrl (lower): embryonic day 12.5; Dnm1ltm1.1Hise/? (more )
Note: Double labeled: green - Casp3; red - MHC.
Structure Level Pattern Image Note
TS20: heart left ventricle Present 2C Ctrl (lower left merge)
Specimen 2C Mut (lower): embryonic day 12.5; Dnm1ltm1.1Hise/Dnm1ltm1.1Hise, Tg(Mef2c-cre)2Blk/0 (more )
Note: Conditional mutant. Double labeled: green - Casp3; red - MHC.
Structure Level Pattern Image Note
TS20: heart left ventricle Present 2C Mut (lower right merge) Authors report no survival defect was observed.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory