Olig2 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:173287 Long JE, et al., Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways. J Comp Neurol. 2009 Feb 1;512(4):556-72
Assay type:	RNA in situ
MGI Accession ID:	MGI:7466526
Gene symbol:	Olig2
Gene name:	oligodendrocyte transcription factor 2

Probe:	Olig2 probe
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

Specimen Table 3 WT: embryonic day 15.5 (more

)
Note: The genetic background of the specimen was either wild type or heterozygous.

Structure	Level	Pattern	Image	Note
TS23: lateral ganglionic eminence	Present

Specimen Table 3 Dlx1&2-/-: embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more

)

Structure	Level	Pattern	Image	Note
TS23: lateral ganglionic eminence	Present	Regionally restricted		Expression was upregulated in the subventricular zone. Expression was unchanged in the ventricular zone. It was undetectable in the mantle zone.

Specimen Table 4 D: embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more

)

Structure	Level	Pattern	Image	Note
TS23: lateral ganglionic eminence	Present	Regionally restricted		Expression was increased in the subventricular zone. Expression was unchanged in the ventricular zone. It was undetectable in the mantle zone.
TS23: telencephalon septum	Present	Regionally restricted		Expression was unchanged in the ventricular zone. It was undetectable in the subventricular zone and mantle zone.

Specimen Table 4 M: embryonic day 15.5; Ascl1^tm1And/Ascl1^tm1And (more

)

Structure	Level	Pattern	Image	Note
TS23: lateral ganglionic eminence	Present	Regionally restricted		Expression was severely decreased in the ventricular zone. It was undetectable in the subventricular zone and mantle zone.
TS23: telencephalon septum	Present	Regionally restricted		Expression was severely decreased in the ventricular zone. It was undetectable in the subventricular zone and mantle zone.

Specimen Table 4 DM: embryonic day 15.5; Ascl1^tm1And/Ascl1^tm1And, Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more

)

Structure	Level	Pattern	Image	Note
TS23: lateral ganglionic eminence	Present	Regionally restricted		Expression was increased in the subventricular zone. Expression was unchanged in the ventricular zone. It was undetectable in the mantle zone.
TS23: telencephalon septum	Weak	Regionally restricted		Expression was severely decreased in the ventricular zone. It was undetectable in the subventricular zone and mantle zone.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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