Gene Expression Data
Assay Details
Assay
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Reference:
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J:184591
Aoyama M, et al., Spatial Restriction of Bone Morphogenetic Protein Signaling in Mouse Gastrula through the mVam2-Dependent Endocytic Pathway. Dev Cell. 2012 Jun 12;22(6):1163-75
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7464811
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Gene symbol:
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Bmp4
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Gene name:
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bone morphogenetic protein 4
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Probe:
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Bmp4 probe
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
4 Bmp4 E6.5 WT:
embryonic day 6.5
(more )
Specimen
4 Bmp4 E6.5 WT:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 6.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Structure |
Level |
Pattern |
Image |
Note |
TS9: extraembryonic component |
Present |
Regionally restricted |
4_Bmp4 E6.5 WT
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Expression in extraembryonic mesoderm.
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Specimen
4 Bmp4 E6.5 -/-:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Vps41tm1.1Ywd/Vps41tm1.1Ywd
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Age:
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embryonic day 6.5
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Sex:
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Not Specified
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Type:
|
whole mount
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Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS9: extraembryonic component |
Present |
Regionally restricted |
4_Bmp4 E6.5 -/-
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Expression localized more distally than in wild type.
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Specimen
4 Bmp4 E7.5 WT:
embryonic day 7.5
(more )
Specimen
4 Bmp4 E7.5 WT:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 7.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
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Fixation:
|
4% Paraformaldehyde
|
Specimen
4 Bmp4 E7.5 -/-:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
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Vps41tm1.1Ywd/Vps41tm1.1Ywd
|
Age:
|
embryonic day 7.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS11: extraembryonic mesoderm |
Present |
Regionally restricted |
4_Bmp4 E7.5 -/-
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Expression localized more distally than in wild type.
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TS11: embryo |
Present |
Regionally restricted |
4_Bmp4 E7.5 -/-
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Expression in proximal region of embryo, similar to that of wild type.
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Specimen
4 Bmp4 E8.5 -/-:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Vps41tm1.1Ywd/Vps41tm1.1Ywd
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Age:
|
embryonic day 8.5
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Sex:
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Not Specified
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Type:
|
whole mount
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Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS13: extraembryonic mesenchyme |
Present |
Regionally restricted |
4_Bmp4 E8.5 -/-
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Expression localized more distally than in wild type.
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TS13: embryo |
Present |
Regionally restricted |
4_Bmp4 E8.5 -/-
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Expression in proximal region of embryo.
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