Ctnnb1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:226036 Maddala R, et al., Rap1 GTPase is required for mouse lens epithelial maintenance and morphogenesis. Dev Biol. 2015 Oct 1;406(1):74-91
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7464649
Gene symbol:	Ctnnb1
Gene name:	catenin beta 1

Antibody:	anti-beta-catenin
Detection system:	Secondary antibody coupled to Alexa Fluor 594

Results

5A E13.5 WT ©

Specimen 5A E13.5 WT: embryonic day 13.5 (more

)

Structure	Level	Pattern	Image	Note
TS21: lens epithelium	Present		5A E13.5 WT	Expressed at the cell-cell junctions.
TS21: lens fiber	Present		5A E13.5 WT	Expressed at the cell-cell junctions.

5A E13.5 cKO ©

Specimen 5A E13.5 cKO: embryonic day 13.5; Rap1a^tm1Morz/Rap1a^tm1Morz, Rap1b^tm1Morz/Rap1b^tm1Morz, Tg(Pax6-cre,GFP)1Pgr/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS21: lens epithelium	Present		5A E13.5 cKO	Reduced expression compared with the control.
TS21: lens fiber	Present		5A E13.5 cKO	Reduced expression compared with the control.

5A E15.5 WT ©

Specimen 5A E15.5 WT: embryonic day 15.5 (more

)

Structure	Level	Pattern	Image	Note
TS23: lens epithelium	Present		5A E15.5 WT	Expressed at the cell-cell junctions.
TS23: lens fiber	Present		5A E15.5 WT	Expressed at the cell-cell junctions.

5A E15.5 cKO ©

Specimen 5A E15.5 cKO: embryonic day 15.5; Rap1a^tm1Morz/Rap1a^tm1Morz, Rap1b^tm1Morz/Rap1b^tm1Morz, Tg(Pax6-cre,GFP)1Pgr/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS23: lens epithelium	Present		5A E15.5 cKO	Progressive and dramatic reduction in expression was seen.
TS23: lens fiber	Present		5A E15.5 cKO	Progressive and dramatic reduction in expression was seen.

5A E17.5 WT ©

Specimen 5A E17.5 WT: embryonic day 17.5 (more

)

Structure	Level	Pattern	Image	Note
TS25: lens epithelium	Present		5A E17.5 WT	Expressed at the cell-cell junctions.
TS25: lens fiber	Present		5A E17.5 WT	Expressed at the cell-cell junctions.

5A E17.5 cKO ©

Specimen 5A E17.5 cKO: embryonic day 17.5; Rap1a^tm1Morz/Rap1a^tm1Morz, Rap1b^tm1Morz/Rap1b^tm1Morz, Tg(Pax6-cre,GFP)1Pgr/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS25: lens epithelium	Weak		5A E17.5 cKO	Progressive and dramatic reduction in expression was seen.
TS25: lens fiber	Weak		5A E17.5 cKO	Progressive and dramatic reduction in expression was seen.

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