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Gene Expression Data
Assay Details
Assay
Reference: J:173287 Long JE, et al., Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways. J Comp Neurol. 2009 Feb 1;512(4):556-72
Assay type: RNA in situ
MGI Accession ID: MGI:7464514
Gene symbol: Gad1
Gene name: glutamate decarboxylase 1
Probe: Gad67 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Table 4 data was incorporated into Fig. 7 & S2 samples, as per the text.
Results
Specimen 6g: embryonic day 15.5 (more )
Note: littermate control; the genetic background of the specimen is either +/+ or +/-
Structure Level Pattern Image Note
TS23: corpus striatum Present Regionally restricted 6g Expression marks the striatal differentiated state.
Specimen 6g': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: corpus striatum Weak Regionally restricted 6g' Expression was decreased in the striatum. Residual expression was seen in superficial parts of the striatal mantle.
Specimen 7l: embryonic day 15.5 (more )
Note: littermate control; the genetic background of the specimen is either +/+ or +/-
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present S2e , 7l
TS23: telencephalon septum Present S2e , 7l
Specimen 7l': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence mantle zone Weak Regionally restricted 7l' , S2e' Expression was severely decreased in the subventricular zone and mantle zone.
TS23: lateral ganglionic eminence subventricular zone Weak Regionally restricted 7l' , S2e' Expression was severely decreased in the subventricular zone and mantle zone.
TS23: lateral ganglionic eminence ventricular zone Absent 7l' , S2e'
TS23: telencephalon septum Present Regionally restricted 7l' , S2e' Expression was unchanged in the subventricular zone and mantle zone. It was undetectable in the ventricular zone.
Specimen 7l'': embryonic day 15.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence subventricular zone Present S2e'' , 7l'' Expression was increased in the subventricular zone.
TS23: lateral ganglionic eminence mantle zone Present S2e'' , 7l'' Expression was unchanged in the mantle zone.
TS23: lateral ganglionic eminence ventricular zone Absent 7l'' , S2e''
TS23: telencephalon septum Present Regionally restricted S2e'' , 7l'' Expression was unchanged in the dorsal subventricular zone and mantle zone. Expression was moderately/mildly decreased in the ventral subventricular zone and mantle zone. It was undetectable in the ventricular zone.
Specimen 7l''': embryonic day 15.5; Ascl1tm1And/Ascl1tm1And, Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Weak 7l''' Expression was severely decreased in the subventricular zone and mantle zone.
TS23: lateral ganglionic eminence mantle zone Weak 7l''' Expression was severely decreased in the subventricular zone and mantle zone.
TS23: lateral ganglionic eminence ventricular zone Absent 7l'''
TS23: telencephalon septum Weak Regionally restricted 7l''' Expression was severely decreased in the subventricular zone and mantle zone. It was undetectable in the ventricular zone.
Specimen S1g: embryonic day 12.5 (more )
Note: littermate control; the genetic background of the specimen is either +/+ or +/-
Structure Level Pattern Image Note
TS20: telencephalon Present S1g
Specimen S1g': embryonic day 12.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS20: telencephalon Present S1g'
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory