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Gene Expression Data
Assay Details
Assay
Reference: J:173287 Long JE, et al., Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways. J Comp Neurol. 2009 Feb 1;512(4):556-72
Assay type: RNA in situ
MGI Accession ID: MGI:7464498
Gene symbol: Lmo4
Gene name: LIM domain only 4
Probe: Lmo4 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Table 4 data was incorporated into Fig. 7 & S2 samples, as per the text.
Results
Specimen 5q: embryonic day 15.5 (more )
Note: The genetic background of the specimen was either wild type or heterozygous.
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Strong Regionally restricted 5q Expression was detected in the subventricular zone and mantle zone.
TS23: olfactory tubercle Present 5q

Specimen 5q': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Strong Regionally restricted 5q' Expression remained strong in the dorsal and ventral lateral ganglionic eminence in the mutant.
TS23: olfactory tubercle Absent 5q'

Specimen 7i: embryonic day 15.5 (more )
Note: The genetic background of the specimen was either wild type or heterozygous.
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present 7i , S2m

Specimen 7i': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present Regionally restricted S2m' , 7i' Expression was moderately/mildly decreased in the subventricular zone and mantle zone. It was undetectable in the ventricular zone.

Specimen 7i'': embryonic day 15.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Weak Regionally restricted S2m'' , 7i'' Expression was severely decreased in the ventral subventricular zone (unchanged in dorsal SVZ) and mantle zone. It was undetectable in the ventricular zone.

Specimen 7i''': embryonic day 15.5; Ascl1tm1And/Ascl1tm1And, Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Weak Regionally restricted 7i''' Expression was severely decreased in the subventricular zone and mantle zone. It was undetectable in the ventricular zone.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory