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Gene Expression Data
Assay Details
Assay
Reference: J:173287 Long JE, et al., Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways. J Comp Neurol. 2009 Feb 1;512(4):556-72
Assay type: RNA in situ
MGI Accession ID: MGI:7464485
Gene symbol: Arx
Gene name: aristaless related homeobox
Probe: Arx cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Table 3 & 4 data was incorporated into the annotations.
Results
Specimen 5g: embryonic day 15.5 (more )
Note: The genetic background of the specimen was either wild type or heterozygous.
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present Regionally restricted 5g Expression was detected in the subventricular zone and mantle zone.

Specimen 5g': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present Regionally restricted 5g' Expression continued in the subventricular zone and mantle zone of the mutant.

Specimen 7h: embryonic day 15.5 (more )
Note: The genetic background of the specimen was either wild type or heterozygous.
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present S2g , 7h
TS23: telencephalon septum Present S2g , 7h

Specimen 7h': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present Regionally restricted S2g' , 7h' Expression was moderately/mildly decreased in the ventricular zone, subventricular zone, and mantle zone.
TS23: telencephalon septum Present Regionally restricted S2g' , 7h' Expression was moderately/mildly decreased in the ventral subventricular zone and mantle zone. Expression was unchanged in the ventricular zone.

Specimen 7h'': embryonic day 15.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present Regionally restricted 7h'' , S2g'' Expression was increased in the ventricular zone and ventral subventricular zone. Expression was unchanged in the mantle zone.
TS23: telencephalon septum Weak Regionally restricted S2g'' , 7h'' Expression was severely decreased in the ventricular zone, ventral subventricular zone, and mantle zone.

Specimen 7h''': embryonic day 15.5; Ascl1tm1And/Ascl1tm1And, Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Weak Regionally restricted 7h''' Expression was severely decreased in the ventricular zone, subventricular zone, and mantle zone.
TS23: telencephalon septum Weak Regionally restricted 7h''' Expression was severely decreased in the ventricular zone, ventral subventricular zone, and mantle zone.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory