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Gene Expression Data
Assay Details
Assay
Reference: J:173287 Long JE, et al., Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways. J Comp Neurol. 2009 Feb 1;512(4):556-72
Assay type: RNA in situ
MGI Accession ID: MGI:7464448
Gene symbol: Six3
Gene name: sine oculis-related homeobox 3
Probe: Six3 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1o: embryonic day 15.5 (more )
Note: The genetic background of the specimen was either wild type or heterozygous.
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present 1o

Specimen 1o': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Weak Regionally restricted 1o' Expression was greatly reduced in the mutant dorsal lateral ganglionic eminence.

Specimen 5t: embryonic day 15.5 (more )
Note: The genetic background of the specimen was either wild type or heterozygous.
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present Regionally restricted 5t Expression was detected in the subventricular zone and mantle zone.
TS23: olfactory tubercle Present 5t

Specimen 5t': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present Regionally restricted 5t' Expression continued in the subventricular zone and mantle zone of the mutant.
TS23: olfactory tubercle Absent 5t'

Specimen S2f: embryonic day 15.5 (more )
Note: The genetic background of the specimen was either wild type or heterozygous.
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present S2f
TS23: telencephalon septum Present S2f

Specimen S2f': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present Regionally restricted S2f' Expression was increased in the ventricular zone. Expression was severely decreased in the dorsal subventricular zone and mantle zone.
TS23: telencephalon septum Present Regionally restricted S2f' Expression was increased in the ventricular zone and subventricular zone. Expression was unchanged in the mantle zone.

Specimen S2f'': embryonic day 15.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present Regionally restricted S2f'' Expression was unchanged in the ventricular zone. Expression was severely decreased in the ventral subventricular zone and mantle zone.
TS23: telencephalon septum Present S2f'' Expression was unchanged in the ventricular zone, subventricular zone, and mantle zone.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory