Meis2 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:173287 Long JE, et al., Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways. J Comp Neurol. 2009 Feb 1;512(4):556-72
Assay type:	RNA in situ
MGI Accession ID:	MGI:7464444
Gene symbol:	Meis2
Gene name:	Meis homeobox 2

Probe:	Meis2 cDNA
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

1l ©

Specimen 1l: embryonic day 15.5 (more

)
Note: littermate control; the genetic background of the specimen is either +/+ or +/-

Structure	Level	Pattern	Image	Note
TS23: lateral ganglionic eminence	Present		1l

1l' ©

Specimen 1l': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more

)

Structure	Level	Pattern	Image	Note
TS23: lateral ganglionic eminence	Weak	Regionally restricted	1l'	Expression was greatly reduced in the mutant dorsal lateral ganglionic eminence.

5r ©

Specimen 5r: embryonic day 15.5 (more

)
Note: littermate control; the genetic background of the specimen is either +/+ or +/-

Structure	Level	Pattern	Image	Note
TS23: lateral ganglionic eminence mantle zone	Present		5r
TS23: lateral ganglionic eminence subventricular zone	Present		5r

5r' ©

Specimen 5r': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more

)

Structure	Level	Pattern	Image	Note
TS23: lateral ganglionic eminence	Present	Regionally restricted	5r'	Expression was reduced particularly in parts related to the dorsal lateral ganglionic eminence.
TS23: lateral ganglionic eminence mantle zone	Present		5r'
TS23: lateral ganglionic eminence subventricular zone	Present		5r'

S2c ©

Specimen S2c: embryonic day 15.5 (more

)
Note: littermate control; the genetic background of the specimen is either +/+ or +/-

Structure	Level	Pattern	Image	Note
TS23: lateral ganglionic eminence	Present		S2c
TS23: telencephalon septum	Present		S2c

S2c' ©

Specimen S2c': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more

)

Structure	Level	Pattern	Image	Note
TS23: lateral ganglionic eminence	Present		S2c'	Expression was unchanged in the ventricular zone.
TS23: lateral ganglionic eminence mantle zone	Weak	Regionally restricted	S2c'	Expression was severely decreased in the subventricular zone and ventral mantle zone.
TS23: lateral ganglionic eminence subventricular zone	Weak	Regionally restricted	S2c'	Expression was severely decreased in the subventricular zone and ventral mantle zone.
TS23: telencephalon septum	Present	Regionally restricted	S2c'	Expression was unchanged in the ventricular zone, subventricular zone, and mantle zone.

S2c'' ©

Specimen S2c'': embryonic day 15.5; Ascl1^tm1And/Ascl1^tm1And (more

)

Structure	Level	Pattern	Image	Note
TS23: lateral ganglionic eminence mantle zone	Present	Regionally restricted	S2c''	Expression was unchanged in the ventricular zone and mantle zone.
TS23: lateral ganglionic eminence ventricular zone	Present	Regionally restricted	S2c''	Expression was unchanged in the ventricular zone and mantle zone.
TS23: lateral ganglionic eminence subventricular zone	Present	Regionally restricted	S2c''	Expression was unchanged in the dorsal subventricular zone and moderately/mildly decreased in the ventral subventricular zone.
TS23: telencephalon septum	Present	Regionally restricted	S2c''	Expression was unchanged in the ventricular zone and dorsal subventricular zone. Expression was severely decreased in the ventral subventricular zone and mantle zone.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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