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Gene Expression Data
Assay Details
Assay
Reference: J:173287 Long JE, et al., Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways. J Comp Neurol. 2009 Feb 1;512(4):556-72
Assay type: RNA in situ
MGI Accession ID: MGI:7464434
Gene symbol: Dlx5
Gene name: distal-less homeobox 5
Probe: Dlx5 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Table 4 data was incorporated into Fig. 7 &S2 samples, as per the text.
Results
Specimen 1c: embryonic day 15.5 (more )
Note: The genetic background of the specimen was either wild type or heterozygous.
Structure Cell Type Level Pattern Image Note
TS23: lateral ganglionic eminence Present 1c
TS23: telencephalon septum neuron Present 1c

Specimen 1c': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Cell Type Level Pattern Image Note
TS23: lateral ganglionic eminence Absent 1c'
TS23: telencephalon septum neuron Present 1c' Expression was maintained or increased in septal neurons.

Specimen 7f: embryonic day 15.5 (more )
Note: The genetic background of the specimen was either wild type or heterozygous.
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present S2d , 7f
TS23: telencephalon septum Present S2d , 7f

Specimen 7f': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Weak Regionally restricted S2d' , 7f' Expression was severely decreased in the subventricular zone and mantle zone. Expression was undetectable in the ventricular zone.
TS23: telencephalon septum Present Regionally restricted S2d' , 7f' Expression was increased in the mantle zone and unchanged in the subventricular zone. Expression was undetectable in the ventricular zone.

Specimen 7f'': embryonic day 15.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present Regionally restricted S2d'' , 7f'' Expression was increased in the subventricular zone and mantle zone. Expression was undetectable in the ventricular zone.
TS23: telencephalon septum Present Regionally restricted 7f'' , S2d'' Expression was increased in the mantle zone and unchanged in the subventricular zone. Expression was undetectable in the ventricular zone.

Specimen 7f''': embryonic day 15.5; Ascl1tm1And/Ascl1tm1And, Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Weak Regionally restricted 7f''' Expression was severely decreased in the subventricular zone and mantle zone. Expression was undetectable in the ventricular zone.
TS23: telencephalon septum Weak Regionally restricted 7f''' Expression was severely decreased in the subventricular zone and mantle zone. Expression was undetectable in the ventricular zone.

Specimen S1c: embryonic day 12.5 (more )
Note: The genetic background of the specimen was either wild type or heterozygous.
Structure Level Pattern Image Note
TS20: lateral ganglionic eminence Present S1c

Specimen S1c': embryonic day 12.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS20: lateral ganglionic eminence Absent S1c'


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory