Gene Expression Data
Assay Details
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Assay
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Reference:
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J:173287
Long JE, et al., Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways. J Comp Neurol. 2009 Feb 1;512(4):556-72
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7464433
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Gene symbol:
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Dlx2
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Gene name:
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distal-less homeobox 2
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Probe:
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Dlx2 cDNA
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Assay notes:
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The probe recognized the truncated transcript in the mutant.
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Results
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Specimen
1b:
embryonic day 15.5
(more  )
Note: The genetic background of the specimen
was either wild type or heterozygous.
Specimen
1b:
(close  )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6J
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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The genetic background of the specimen
was either wild type or heterozygous.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: lateral ganglionic eminence |
Present |
Graded |
1b
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Expressed in a dorsoventral grandient in progenitor cells of the lateral ganglionic eminence. Expression was particularly high in the dorsal LGE, where it was detected in most cells in both the ventricular and subventricular zones.
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| TS23: telencephalon septum |
Present |
Graded |
1b
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Expressed in a dorsoventral grandient.
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Specimen
1b':
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: lateral ganglionic eminence |
Weak |
Regionally restricted |
1b'
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Dorsal lateral ganglionic eminence was not labeled. Low levels were detected in the subventricular zone of the ventral LGE.
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| TS23: telencephalon septum |
Weak |
Regionally restricted |
1b'
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Dorsal septum was not labeled. Low levels were detected in ventral septum.
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Specimen
S1b:
embryonic day 12.5
(more )
Note: The genetic background of the specimen
was either wild type or heterozygous.
Specimen
S1b:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6J
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
|
|
Note:
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The genetic background of the specimen
was either wild type or heterozygous.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS20: lateral ganglionic eminence |
Present |
Regionally restricted |
S1b
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Expressed in a dorsoventral grandient in progenitor cells of the lateral ganglionic eminence.
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Specimen
S1b':
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: lateral ganglionic eminence |
Weak |
Regionally restricted |
S1b'
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Dorsal lateral ganglionic eminence was not labeled. Low levels were detected in the subventricular zone of the ventral LGE.
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Analysis Tools