Bmp4 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:203791 Kuracha MR, et al., Spry1 and Spry2 are necessary for eyelid closure. Dev Biol. 2013 Nov 15;383(2):227-38
Assay type:	RNA in situ
MGI Accession ID:	MGI:7464158
Gene symbol:	Bmp4
Gene name:	bone morphogenetic protein 4

Probe:	Bmp4 cDNA
Probe preparation:	Antisense labelled with S35 RNA
Visualized with:	Autoradiography

Results

6A ©

6A' ©

Specimen 6A/A': embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: eyelid mesenchyme	Present	Clusters	6A' , 6A	Expression was localized to a cluster of mesenchymal cells near the margin that were immediately adjacent to Shh-positive cells in the palpebral conjunctival epithelium.

6B ©

6B' ©

Specimen 6B/B': embryonic day 14.5; Spry1^tm1Jdli/Spry1^tm1Jdli, Spry2^tm1Mrt/Spry2^tm1Mrt, Tg(Pax6-cre,GFP)1Pgr/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS22: eyelid mesenchyme	Present		6B' , 6B	A broader domain of expression was seen in the mesenchymal cells.
TS22: hair follicle	Present		6B	Similar as in the control.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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