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Gene Expression Data
Assay Details
Assay
Reference: J:277247 Vetrivel S, et al., Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia. Exp Eye Res. 2019 Apr 13;
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7461920
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved Caspase-3 (Asp175; #9661)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 9 C3H E11.5: embryonic day 11.5 (more )
Note: Double labeled: green - Casp3; red - Tfap2a (assay MGI:7461922).
Structure Level Pattern Image Note
TS19: lens vesicle Absent 9_C3H E11.5
Specimen 9 Aey69 E11.5: embryonic day 11.5; Gja8Aey69/Gja8Aey69, H3c14Aey69/H3c14Aey69 (more )
Note: Double labeled: green - Casp3; red - Tfap2a (assay MGI:7461922).
Structure Level Pattern Image Note
TS19: lens vesicle Present Regionally restricted 9_Aey69 E11.5 Expression indicates apoptosis in posterior vesicle cells
Specimen 9 C3H E12.5: embryonic day 12.5 (more )
Note: Double labeled: green - Casp3; red - Tfap2a (assay MGI:7461922).
Structure Level Pattern Image Note
TS20: lens vesicle Absent 9_C3H E12.5
Specimen 9 Aey69 E12.5: embryonic day 12.5; Gja8Aey69/Gja8Aey69, H3c14Aey69/H3c14Aey69 (more )
Note: Double labeled: green - Casp3; red - Tfap2a (assay MGI:7461922).
Structure Level Pattern Image Note
TS20: lens vesicle Present Regionally restricted 9_Aey69 E12.5 Expression indicates apoptosis in posterior vesicle cells
Specimen 9 C3H E13.5: embryonic day 13.5 (more )
Note: Double labeled: green - Casp3; red - Tfap2a (assay MGI:7461922).
Structure Level Pattern Image Note
TS21: lens Absent 9_C3H E13.5
Specimen 9 Aey69 E13.5: embryonic day 13.5; Gja8Aey69/Gja8Aey69, H3c14Aey69/H3c14Aey69 (more )
Note: Double labeled: green - Casp3; red - Tfap2a (assay MGI:7461922).
Structure Level Pattern Image Note
TS21: lens Present Regionally restricted 9_Aey69 E13.5 Expression indicates apoptosis in posterior vesicle cells
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
MGI 6.24 		The Jackson Laboratory