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Gene Expression Data
Assay Details
Assay
Reference: J:164315 Vanden Bosch A, et al., NuSAP is essential for chromatin-induced spindle formation during early embryogenesis. J Cell Sci. 2010 Oct 1;123(Pt 19):3244-55
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7451167
Gene symbol: Nusap1
Gene name: nucleolar and spindle associated protein 1
Antibody: anti-NuSAP(p)
Results
Specimen 1E: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: crypt of lieberkuhn keratinocyte Present 1E
TS28: epidermis basal layer keratinocyte Present 1E
TS28: intestinal villus Trace Regionally restricted 1E Expression is in the crypts of Lieberkuhn and the absorptive epithelial cells of the villi and cells of the lamina propria, the supporting layer underlying the intestinal epithelium, showed little or no expression.
TS28: intestine lamina propria Trace Regionally restricted 1E Expression is in the crypts of Lieberkuhn and the absorptive epithelial cells of the villi and cells of the lamina propria, the supporting layer underlying the intestinal epithelium, showed little or no expression.

Specimen 1G: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: epidermis basal layer keratinocyte Present Regionally restricted 1G NuSAP Expression is in keratinocytes.
TS28: hair outer root sheath keratinocyte Present Regionally restricted 1G NuSAP Expression is in keratinocytes.
TS28: dermis keratinocyte Present Regionally restricted 1G NuSAP Expression is absent in differentiating keratinocytes and most dermal cells.

Specimen 1H: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: bone marrow Strong 1H NuSAP
TS28: tibia osteocyte Absent 1H NuSAP Expression is absent in the differentiated osteocytes embedded in the bone cortex.

Specimen 1I: postnatal (more )
Structure Cell Type Level Pattern Image Note
TS28: primary spermatocyte Strong 1I right , 1I left
TS28: spermatogonium Trace 1I left , 1I right There is little or no staining.
TS28: interstitium of the testis Absent 1I right , 1I left
TS28: seminiferous tubule epithelium Absent 1I right , 1I left
TS28: Sertoli cell Sertoli cell Absent 1I left , 1I right

Specimen 2E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: embryo Present Ubiquitous 2E
TS21: brain Present 2E
TS21: heart Present 2E
TS21: liver Present 2E
TS21: lung Present 2E
TS21: metanephros Present 2E
TS21: trunk Present Regionally restricted 2E Expression is in the spine.

Specimen 2F: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: esophagus epithelium Present Regionally restricted 2F NuSAP Expression is in the endodermal epithelium.
TS21: trachea epithelium Present Regionally restricted 2F NuSAP Expression is in the endodermal epithelium.
TS21: esophagus Present Regionally restricted 2F NuSAP Expression is in the mesodermal cells that give rise to the lamina propria, the muscularis mucosae, the submucosa, the circular and longitudinal muscle layers and the outer mesothelial layer.
TS21: trachea Present Regionally restricted 2F NuSAP Expression is in the mesodermal cells that give rise to the lamina propria, the muscularis mucosae, the submucosa, the circular and longitudinal muscle layers and the outer mesothelial layer.

Specimen 2G: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: stomach epithelium Present 2G NuSAP Expression is in the endodermal epithelium.
TS21: stomach Present Regionally restricted 2G NuSAP Expression is in the mesodermal cells that give rise to the lamina propria, the muscularis mucosae, the submucosa, the circular and longitudinal muscle layers and the outer mesothelial layer.

Specimen 2H: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: brain Present Regionally restricted 2H NuSAP Expression is adjacent to the ventricles where proliferating cells are located.

Specimen 2I: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: bone columnar chondrocyte Present Regionally restricted 2I NuSAP Expression is restricted to the region of the periarticular and columnar chondrocytes, and was absent from the hypertrophic zone.
TS26: bone growth plate cartilage chondrocyte Present Regionally restricted 2I NuSAP Expression is restricted to the region of the periarticular and columnar chondrocytes, and was absent from the hypertrophic zone.

Specimen 2J: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: bone columnar chondrocyte Present Regionally restricted 2J Expression is restricted to the region of the periarticular and columnar chondrocytes, and was absent from the hypertrophic zone.
TS26: bone growth plate cartilage chondrocyte Present Regionally restricted 2J Expression is restricted to the region of the periarticular and columnar chondrocytes, and was absent from the hypertrophic zone.

Specimen S1B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lung Present S1B

Specimen S1C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: pancreas Present S1C

Specimen S1D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: heart Present S1D

Specimen S1E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: metanephros Present S1E


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory