Gene Expression Data
Assay Details
Assay
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Reference:
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J:195901
Ehlen H, Inactivation of anoctamin-6/Tmem16f, a regulator of phosphatidylserine scrambling in osteoblasts, leads to decreased mineral deposition in skeletal tissues. J Bone Miner Res. 2013;28(2):246-59
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7451032
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Gene symbol:
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Sp7
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Gene name:
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Sp7 transcription factor 7
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Probe:
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Osx probe
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Probe preparation:
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Antisense labelled with P33 RNA
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Results
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Specimen
4C ctrl:
embryonic day 14.5
(more )
Specimen
4C ctrl:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS22: forelimb cartilage condensation |
hypertrophic chondrocyte |
Present |
Regionally restricted |
4C ctrl
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Expression is in terminal hypertrophic chondrocytes.
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TS22: perichondrium |
osteoblast |
Present |
Regionally restricted |
4C ctrl
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Expression is in differentiating osteoblasts of the perichondrium/periosteum flanking the hypertrophic region.
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TS22: periosteum |
osteoblast |
Present |
Regionally restricted |
4C ctrl
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Expression is in differentiating osteoblasts of the perichondrium/periosteum flanking the hypertrophic region.
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Specimen
4C -/-:
(close )
Genetic Background:
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B6.129-Ano6tm1Avor
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Mutant Allele(s):
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Ano6tm1Avor/Ano6tm1Avor
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Specimen
not shown ctrl:
embryonic day 16.5
(more )
Specimen
not shown ctrl:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS24: forelimb cartilage condensation |
hypertrophic chondrocyte |
Present |
Regionally restricted |
|
Expression is in terminal hypertrophic chondrocytes.
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TS24: perichondrium |
osteoblast |
Present |
Regionally restricted |
|
Expression is in differentiating osteoblasts of the perichondrium/periosteum flanking the hypertrophic region.
|
TS24: periosteum |
osteoblast |
Present |
Regionally restricted |
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Expression is in differentiating osteoblasts of the perichondrium/periosteum flanking the hypertrophic region.
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Specimen
not shown -/-:
(close )
Genetic Background:
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B6.129-Ano6tm1Avor
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Mutant Allele(s):
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Ano6tm1Avor/Ano6tm1Avor
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
|
section
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Embedding:
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Paraffin
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS24: forelimb cartilage condensation |
hypertrophic chondrocyte |
Present |
Regionally restricted |
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Expression in this mutant is similar to controls.
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TS24: perichondrium |
osteoblast |
Present |
Regionally restricted |
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Expression in this mutant is similar to controls.
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TS24: periosteum |
osteoblast |
Present |
Regionally restricted |
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Expression in this mutant is similar to controls.
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