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Gene Expression Data
Assay Details
Assay
Reference: J:334174 Wang Y, et al., Melanocortin 4 receptor signals at the neuronal primary cilium to control food intake and body weight. J Clin Invest. 2021 May 3;131(9)
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7449351
Gene symbol: Mc4r
Gene name: melanocortin 4 receptor
Reporter: GFP
Antibody: anti-GFP (ab13970)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1 - P2: postnatal day 2; Mc4rem1Vai/Mc4rem1Vai (more )
Note: Double labeled: green - Mc4r; red - Adcy3 (assay MGI:7449357).
Structure Cell Type Level Pattern Image Note
TS27: brain central nervous system neuron Present Regionally restricted 1_P2 MC4R-GFP , 1_P2 Merged Expression is seen in the neuronal primary cilia.
Specimen 1 - P6: postnatal day 6; Mc4rem1Vai/Mc4rem1Vai (more )
Note: Double labeled: green - Mc4r; red - Adcy3 (assay MGI:7449357).
Structure Cell Type Level Pattern Image Note
TS28: brain central nervous system neuron Present Regionally restricted 1_P6 MC4R-GFP , 1_P6 Merged Expression is seen in the neuronal primary cilia.
Specimen 1 - P11: postnatal day 11; Mc4rem1Vai/Mc4rem1Vai (more )
Note: Double labeled: green - Mc4r; red - Adcy3 (assay MGI:7449357).
Structure Cell Type Level Pattern Image Note
TS28: brain central nervous system neuron Present Regionally restricted 1_P11 Merged , 1_P11 MC4R-GFP Expression is seen in the neuronal primary cilia.
Specimen 1 - P15: postnatal day 15; Mc4rem1Vai/Mc4rem1Vai (more )
Note: Double labeled: green - Mc4r; red - Adcy3 (assay MGI:7449357).
Structure Cell Type Level Pattern Image Note
TS28: brain central nervous system neuron Present Regionally restricted 1_P15 MC4R-GFP , 1_P15 Merged Expression is seen in the neuronal primary cilia.
Specimen 1 - Adult: postnatal adult; Mc4rem1Vai/Mc4rem1Vai (more )
Note: Double labeled: green - Mc4r; red - Adcy3 (assay MGI:7449357).
Structure Cell Type Level Pattern Image Note
TS28: brain central nervous system neuron Present Regionally restricted 1_Adult Merged , 1_Adult MC4R-GFP Expression is seen in the neuronal primary cilia.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/09/2025
MGI 6.24 		The Jackson Laboratory