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Gene Expression Data
Assay Details
Assay
Reference: J:316150 Li R, et al., A distinct response to endogenous DNA damage in the development of Nbs1-deficient cortical neurons. Cell Res. 2012 May;22(5):859-72
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7448694
Gene symbol: H2ax
Gene name: H2A.X variant histone
Antibody: anti-gammaH2AX
Detection system: Secondary antibody
Results
Specimen 2A CNS-ctr: embryonic day 12.5; Nbntm2Zqw/Nbntm2Zqw (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Ambiguous 2A CNS-ctr Expression in control was not described.
Specimen 2A CNS-del: embryonic day 12.5; Nbntm2Zqw/Nbntm2Zqw, Tg(Nes-cre)1Wme/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS20: cerebral cortex marginal layer neural progenitor cell Present 2A CNS-del Increased expression in proliferating neural precursors at ventricular zone.
TS20: cerebral cortex ventricular layer cerebral cortex neuron Present 2A CNS-del Increased expression in postmitotic neurons in mantle zone.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory