About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:236440 You L, et al., The chromatin regulator Brpf1 regulates embryo development and cell proliferation. J Biol Chem. 2015 May 1;290(18):11349-64
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7447071
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: Anti-Sox2 (Clone 245610; MAB2018)
Detection system: Secondary antibody coupled to Cy3
Assay notes: Fixation was with 12% glacial acetic acid.
Results
Specimen 5A Control: embryonic day 9.5; Brpf1tm1c(EUCOMM)Wtsi/Brpf1+ (more )
Structure Cell Type Level Pattern Image Note
TS15: neural tube neural progenitor cell Present Uniform 5A Control w/DAPI , 5A Control Expression in neural precursors.
Specimen 5A Brdf1 delta/delta: embryonic day 9.5; Brpf1tm1c(EUCOMM)Wtsi/Brpf1tm1c(EUCOMM)Wtsi, Tg(EIIa-cre)C5379Lmgd/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted 5A Brpf1 delta/delta , 5A Brpf1 delta/delta w/DAPI Expression uneven compared to control. Smaller population of expressing cells. Loss of expression in ventral part of neural tube.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory