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Gene Expression Data
Assay Details
Assay
Reference: J:310178 Efimenko E, et al., The transcription factor GATA4 is required for follicular development and normal ovarian function. Dev Biol. 2013 Sep 1;381(1):144-58
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7446511
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-activated Casp3
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen 8A: postnatal day 90 (more )
Note: Double labeled: red - Casp3; green - Amh (assay MGI:7446419).
Structure Cell Type Level Pattern Image Note
TS28: ovary atretic follicle granulosa cell Present 8A
TS28: follicle cell of tertiary follicle granulosa cell Trace 8A Very few positive cells in early antral or antral follicle.
Specimen 8B: postnatal day 90 (more )
Note: Double labeled: red - Casp3; green - Amh (assay MGI:7446419).
Structure Cell Type Level Pattern Image Note
TS28: follicle cell of antral follicle granulosa cell Trace 8B Very few positive cells in early antral or antral follicle.
TS28: ovary atretic follicle granulosa cell Present 8B
Specimen 8C: postnatal day 90; Gata4tm1.1Wtp/Gata4tm1.1Wtp, Tg(Nr5a1-cre)2Klp/0 (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Amh (assay MGI:7446419).
Structure Cell Type Level Pattern Image Note
TS28: follicle cell of secondary follicle granulosa cell Present 8C preantral follicle
TS28: ovary theca theca cell Present 8C
Specimen 8D: postnatal day 90; Gata4tm1.1Wtp/Gata4tm1.1Wtp, Tg(Nr5a1-cre)2Klp/0 (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Amh (assay MGI:7446419).
Structure Cell Type Level Pattern Image Note
TS28: follicle cell of secondary follicle granulosa cell Present 8D preantral follicle
Specimen 8E: postnatal day 120 (more )
Note: Double labeled: red - Casp3; green - Amh (assay MGI:7446419).
Structure Cell Type Level Pattern Image Note
TS28: follicle cell of antral follicle granulosa cell Trace 8E Very few positive cells in early antral or antral follicle.
TS28: follicle cell of secondary follicle granulosa cell Trace 8E Very few positive cells in preantral follicle.
Specimen 8F: postnatal day 120 (more )
Note: Double labeled: red - Casp3; green - Amh (assay MGI:7446419).
Structure Cell Type Level Pattern Image Note
TS28: follicle cell of antral follicle granulosa cell Trace 8F Very few positive cells in early antral or antral follicle.
TS28: ovary atretic follicle granulosa cell Present 8F
Specimen 8G: postnatal day 120; Gata4tm1.1Wtp/Gata4tm1.1Wtp, Tg(Nr5a1-cre)2Klp/0 (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Amh (assay MGI:7446419).
Structure Cell Type Level Pattern Image Note
TS28: follicle cell of tertiary follicle granulosa cell Present 8G early antral or antral follicle
TS28: ovary theca theca cell Present 8G
Specimen 8H: postnatal day 120; Gata4tm1.1Wtp/Gata4tm1.1Wtp, Tg(Nr5a1-cre)2Klp/0 (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Amh (assay MGI:7446419).
Structure Cell Type Level Pattern Image Note
TS28: follicle cell of secondary follicle granulosa cell Present 8H preantral follicle
Specimen not shown: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: corpus luteum luteal cell Present
Specimen not shown: postnatal adult; Gata4tm1.1Wtp/Gata4tm1.1Wtp, Tg(Nr5a1-cre)2Klp/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: follicle cell of antral follicle granulosa cell Present
TS28: ovary atretic follicle luteal cell Present
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory