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Gene Expression Data
Assay Details
Assay
Reference: J:187742 Mould A, et al., Blimp1/Prdm1 governs terminal differentiation of endovascular trophoblast giant cells and defines multipotent progenitors in the developing placenta. Genes Dev. 2012 Sep 15;26(18):2063-74
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7439098
Gene symbol: Kdr
Gene name: kinase insert domain protein receptor
Reporter: lacZ
Direct Detection
Results
Specimen S1A - Flk1-LacZ - +/+: embryonic day 9.5; Kdrtm1Jrt/Kdr+ (more )
Note: reporter allele paternally inherited
Structure Cell Type Level Pattern Image Note
TS15: extraembryonic blood vessel endothelial cell of placenta Present S2A Flk1-LacZ +/+
TS15: labyrinthine zone endothelial cell of placenta Present S2A Flk1-LacZ +/+
Specimen S1A - Flk1-LacZ - -/-: embryonic day 9.5; Kdrtm1Jrt/Kdr+, Prdm1tm2Rob/Prdm1tm2Rob (more )
Note: reporter allele paternally inherited
Structure Cell Type Level Pattern Image Note
TS15: extraembryonic blood vessel endothelial cell of placenta Present S2A Flk1-LacZ -/- There is reduced vessel complexity in the mutants; the fetal capillaries fail to extend into the labyrinth tissue.
TS15: labyrinthine zone endothelial cell of placenta Present S2A Flk1-LacZ -/- There is reduced vessel complexity in the mutants; the fetal capillaries fail to extend into the labyrinth tissue.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
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