Gene Expression Data
Assay Details
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Assay
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Reference:
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J:187742
Mould A, et al., Blimp1/Prdm1 governs terminal differentiation of endovascular trophoblast giant cells and defines multipotent progenitors in the developing placenta. Genes Dev. 2012 Sep 15;26(18):2063-74
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:7439096
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Gene symbol:
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Prdm1
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Gene name:
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PR domain containing 1, with ZNF domain
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Reporter:
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GFP
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Probe:
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GFP probe
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Probe preparation:
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RNA
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Results
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Specimen
S1A:
embryonic day 7.5; Prdm1tm1Nutt/Prdm1 +
(more  )
Specimen
S1A:
(close  )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Prdm1tm1Nutt/Prdm1+
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Age:
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embryonic day 7.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
S1B:
embryonic day 8.5; Prdm1tm1Nutt/Prdm1 +
(more )
Specimen
S1B:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Prdm1tm1Nutt/Prdm1+
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: ectoplacental cone |
Present |
Regionally restricted |
S1B
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Expression is seen in a subset of cells lying subjacent to the primary trophoblast giant cells as well as in invading spiral artery-associated trophoblast giant cells (SpA-TGCs) above the primary trophoblast giant cell layer.
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Specimen
S1C:
embryonic day 9.5; Prdm1tm1Nutt/Prdm1 +
(more )
Specimen
S1C:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Prdm1tm1Nutt/Prdm1+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: spongiotrophoblast |
Present |
Clusters |
S1C
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Expression is predominantly restricted to small clusters of mature spiral artery-associated trophoblast giant cells (SpA-TGCs) associated with maternal blood vessels.
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Analysis Tools
