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Gene Expression Data
Assay Details
Assay
Reference: J:257197 Elias S, et al., Long-lived unipotent Blimp1-positive luminal stem cells drive mammary gland organogenesis throughout adult life. Nat Commun. 2017 Nov 20;8(1):1714
Assay type: Recombinase reporter
MGI Accession ID: MGI:7438459
Gene symbol: Prdm1
Gene name: PR domain containing 1, with ZNF domain
Reporter: GFP
Antibody: anti-GFP (ab13970)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Assay notes: Intraperitoneal administration of tamoxifen at 4 or 9 weeks in pregnant females for embryonic specimen and pubertal and adult virgin females for postnatal specimen
Results
Specimen Supp1h: embryonic day 16.5; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Prdm1tm5.1(cre/ERT2)Rob/Prdm1+ (more )
Note: Conditional mutant. analysed at 24h post-TAM
Structure Cell Type Level Pattern Image Note
TS24: intestine intestinal epithelial cell Present S1h E16.5 gut intervillous pocket cells (ivc), and forming villus axis (va)
Specimen Supp1i: postnatal week 4; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Prdm1tm5.1(cre/ERT2)Rob/Prdm1+ (more )
Note: Conditional mutant. 72h post-TAM
Structure Cell Type Level Pattern Image Note
TS28: epidermis granular layer hair follicle cell Present S1i 4w skin
TS28: epidermis granular layer hair follicle dermal papilla cell Present S1i 4w skin
TS28: epidermis granular layer hair follicular keratinocyte Present S1i 4w skin
TS28: epidermis granular layer keratinocyte Present S1i 4w skin
TS28: hair follicle hair follicle cell Present S1i 4w skin
TS28: hair follicle hair follicle dermal papilla cell Present S1i 4w skin
TS28: hair follicle hair follicular keratinocyte Present S1i 4w skin
TS28: hair follicle keratinocyte Present S1i 4w skin
TS28: hair follicle dermal papilla hair follicle cell Present S1i 4w skin
TS28: hair follicle dermal papilla hair follicle dermal papilla cell Present S1i 4w skin
TS28: hair follicle dermal papilla hair follicular keratinocyte Present S1i 4w skin
TS28: hair follicle dermal papilla keratinocyte Present S1i 4w skin
TS28: hair inner root sheath hair follicle cell Present S1i 4w skin
TS28: hair inner root sheath hair follicle dermal papilla cell Present S1i 4w skin
TS28: hair inner root sheath hair follicular keratinocyte Present S1i 4w skin
TS28: hair inner root sheath keratinocyte Present S1i 4w skin
TS28: sebaceous gland hair follicle cell Present S1i 4w skin
TS28: sebaceous gland hair follicle dermal papilla cell Present S1i 4w skin
TS28: sebaceous gland hair follicular keratinocyte Present S1i 4w skin
TS28: sebaceous gland keratinocyte Present S1i 4w skin
TS28: skin hair follicle cell Present S1i 4w skin
TS28: skin hair follicle dermal papilla cell Present S1i 4w skin
TS28: skin hair follicular keratinocyte Present S1i 4w skin
TS28: skin keratinocyte Present S1i 4w skin
Specimen Fig1b E13.5: embryonic day 13.5; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Prdm1tm5.1(cre/ERT2)Rob/Prdm1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: exocrine system Present 1b E13.5 in future mammary gland
Specimen Fig1b E15.5: embryonic day 15.5; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Prdm1tm5.1(cre/ERT2)Rob/Prdm1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: exocrine system Present 1b E15.5 in future mammary gland
Specimen Fig1b E18.5: embryonic day 18.5; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Prdm1tm5.1(cre/ERT2)Rob/Prdm1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: mammary gland Present 1b E18.5
Specimen Fig1d E18.5: embryonic day 18.5; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Prdm1tm5.1(cre/ERT2)Rob/Prdm1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: mammary gland Present 1d
Specimen Fig1f P11: postnatal week 11; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Prdm1tm5.1(cre/ERT2)Rob/Prdm1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: mammary gland Present 1f
Specimen Fig1g: postnatal week 11; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Prdm1tm5.1(cre/ERT2)Rob/Prdm1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: mammary gland Present 1g
Specimen Fig1j E18.5: embryonic day 18.5; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Prdm1tm5.1(cre/ERT2)Rob/Prdm1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: mammary gland Present 1j E18.5
Specimen Fig1J 11w: postnatal week 11; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Prdm1tm5.1(cre/ERT2)Rob/Prdm1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: mammary gland Present 1j 11w
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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