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Gene Expression Data
Assay Details
Assay
Reference: J:194470 Davis RB, et al., BRG1 promotes COUP-TFII expression and venous specification during embryonic vascular development. Development. 2013 Mar;140(6):1272-81
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7438439
Gene symbol: Acta2
Gene name: actin alpha 2, smooth muscle, aorta
Antibody: Anti-smooth muscle alpha-Actin (clone 1A4)
Detection system: Cy3
Results
Specimen 3A: embryonic day 10.5 (more )
Note: Double labeled: red - Acta2; green - Pecam1 (assay MGI:7438438).
Structure Cell Type Level Pattern Image Note
TS17: umbilical artery extraembryonic part smooth muscle cell of the umbilical artery Present 3A In controls, the immunopositive cells predominantly accumulated around umbilical arteries.
Specimen 3B: embryonic day 10.5; Smarca4tm1.2Pcn/Smarca4tm1.2Pcn, Tg(Tek-cre)1Ywa/0 (more )
Note: Conditional mutant. Double labeled: red - Acta2; green - Pecam1 (assay MGI:7438438).
Structure Cell Type Level Pattern Image Note
TS17: umbilical artery extraembryonic part smooth muscle cell of the umbilical artery Present 3B In the mutant, immunopositive cells accumulated around both umbilical arteries and veins.
TS17: umbilical vein extraembryonic part smooth muscle cell of the umbilical vein Present 3B In the mutant, immunopositive cells accumulated around both umbilical arteries and veins.
Specimen 3C: embryonic day 10.5 (more )
Note: Double labeled: red - Acta2; green - Pecam1 (assay MGI:7438438).
Structure Cell Type Level Pattern Image Note
TS17: cardinal vein blood vessel smooth muscle cell Absent 3C
Specimen 3D: embryonic day 10.5; Smarca4tm1.2Pcn/Smarca4tm1.2Pcn, Tg(Tek-cre)1Ywa/0 (more )
Note: Conditional mutant. Double labeled: red - Acta2; green - Pecam1 (assay MGI:7438438).
Structure Cell Type Level Pattern Image Note
TS17: cardinal vein blood vessel smooth muscle cell Present 3D
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
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