About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:331512 Kimura S, et al., HIF-2alpha Inhibits Ameloblast Differentiation via Hey2 in Tooth Development. J Dent Res. 2022 Dec;101(13):1637-1644
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7435754
Gene symbol: Hif1a
Gene name: hypoxia inducible factor 1, alpha subunit
Antibody: Anti-Hif-1 alpha (ab2185)
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 1C: embryonic day 13.5 (more )
Note: Mandibular molar tooth germ at the bud stage.
Structure Level Pattern Image Note
TS21: lower jaw molar epithelium Present 1C Expression intensity was higher in the epithelium than in the mesenchyme.
TS21: lower jaw molar mesenchyme Present 1C
Specimen 1G: embryonic day 14.5 (more )
Note: Mandibular molar tooth germ at the cap stage.
Structure Level Pattern Image Note
TS22: lower jaw molar epithelium Strong 1G
TS22: lower jaw molar mesenchyme Weak 1G
Specimen 1K: embryonic day 16.5 (more )
Note: Mandibular molar tooth germ at the bell stage.
Structure Level Pattern Image Note
TS24: lower jaw molar enamel organ Present 1K
TS24: inner enamel epithelium Strong 1K
TS24: lower jaw molar dental papilla Present 1K
Specimen 1O: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lower jaw molar dental papilla Present 1O , 1S
TS26: lower jaw molar enamel organ Present 1O , 1S
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory