About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:243210 Decker RS, et al., Cell origin, volume and arrangement are drivers of articular cartilage formation, morphogenesis and response to injury in mouse limbs. Dev Biol. 2017 Jun 01;426(1):56-68
Assay type: Recombinase reporter
MGI Accession ID: MGI:7435700
Gene symbol: Tg(Dkk3-cre/ERT2)#Mpac
Gene name: transgene insertion, Maurizio Pacifici
Reporter: GFP
Direct Detection
Assay notes: mice received intraperitoneal injections of hydroxytamoxifen at the time noted
Results
Specimen Fig4P0: postnatal day 0; Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tg(Dkk3-cre/ERT2)#Mpac/0 (more )
Note: Conditional mutant. induced once with tamoxifen at E17.5
Structure Level Pattern Image Note
TS27: articular cartilage Present 4Q
TS27: tibia Present 4Q
TS27: posterior cruciate ligament Trace 4S
Specimen Fig4 2mo: postnatal month 2; Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tg(Dkk3-cre/ERT2)#Mpac/0 (more )
Note: Conditional mutant. induced once with tamoxifen at E17.5
Structure Level Pattern Image Note
TS28: articular cartilage Present 4R
TS28: tibia Present 4R
TS28: posterior cruciate ligament Trace 4T
Specimen Fig4P31: postnatal day 31; Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tg(Dkk3-cre/ERT2)#Mpac/0 (more )
Note: Conditional mutant. induced once with tamoxifen at P28
Structure Level Pattern Image Note
TS28: articular cartilage Present 4Y at most superficial layer
TS28: tibia Present 4Y at most superficial layer
TS28: posterior cruciate ligament Present 4Z'
Specimen Fig4 2m 28in: postnatal month 2; Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tg(Dkk3-cre/ERT2)#Mpac/0 (more )
Note: Conditional mutant. induced once with tamoxifen at P28
Structure Level Pattern Image Note
TS28: articular cartilage Present 4Z
TS28: tibia Present 4Z
TS28: posterior cruciate ligament Present 4Z''
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory