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Gene Expression Data
Assay Details
Assay
Reference: J:243210 Decker RS, et al., Cell origin, volume and arrangement are drivers of articular cartilage formation, morphogenesis and response to injury in mouse limbs. Dev Biol. 2017 Jun 01;426(1):56-68
Assay type: Recombinase reporter
MGI Accession ID: MGI:7435698
Gene symbol: Tg(Prg4-cre/ERT2)#Mpac
Gene name: transgene insertion, Maurizio Pacifici
Reporter: tdTomato
Direct Detection
Assay notes: mice received intraperitoneal injections of hydroxytamoxifen at the time noted
Results
Specimen Fig4P0: postnatal day 0; Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tg(Prg4-cre/ERT2)#Mpac/0 (more )
Note: Conditional mutant. induced once with tamoxifen at E17.5
Structure Level Pattern Image Note
TS27: articular cartilage Present 4M
TS27: tibia Present 4M
TS27: posterior cruciate ligament Trace 4O
Specimen Fig4 2mo: postnatal month 2; Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tg(Prg4-cre/ERT2)#Mpac/0 (more )
Note: Conditional mutant. induced once with tamoxifen at E17.5
Structure Level Pattern Image Note
TS28: articular cartilage Present 4N
TS28: tibia Present 4N
TS28: posterior cruciate ligament Trace 4P
Specimen Fig4P31: postnatal day 31; Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tg(Prg4-cre/ERT2)#Mpac/0 (more )
Note: Conditional mutant. induced once with tamoxifen at P28
Structure Level Pattern Image Note
TS28: articular cartilage Present 4U at surface layer
TS28: tibia Present 4U at surface layer
TS28: posterior cruciate ligament Present 4W
Specimen Fig4 2m 28in: postnatal month 2; Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tg(Prg4-cre/ERT2)#Mpac/0 (more )
Note: Conditional mutant. induced once with tamoxifen at P28
Structure Level Pattern Image Note
TS28: articular cartilage Present 4V
TS28: tibia Present 4V
TS28: posterior cruciate ligament Present 4X
Specimen FigS1P0: postnatal day 0; Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tg(Prg4-cre/ERT2)#Mpac/0 (more )
Note: Conditional mutant. induced once with tamoxifen at E17.5
Structure Level Pattern Image Note
TS27: articular cartilage Present S1B
TS27: posterior cruciate ligament Present Single cells S1C less numerous in ligament and enthesis
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory