Gene Expression Data
Assay Details
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Assay
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Reference:
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J:294897
Ankamreddy H, et al., CXCL12 is required for stirrup-shaped stapes formation during mammalian middle ear development. Dev Dyn. 2020 Sep;249(9):1117-1126
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7435275
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Gene symbol:
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Cdon
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Gene name:
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cell adhesion molecule-related/down-regulated by oncogenes
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Probe:
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Cdon cDNA
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
3C:
embryonic day 14.5
(more  )
Specimen
3C:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: skeletal joint |
Present |
Regionally restricted |
3C
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Expression was detected in the middle ear ossicle and inner ear developing joints.
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| TS22: connective tissue |
Present |
Regionally restricted |
3C
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Expression was detected in the middle ear ossicle developing annular ligament.
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Specimen
3F:
(close )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Cxcl12tm1Spo/Cxcl12tm1Spo
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: skeletal joint |
Present |
Regionally restricted |
3F
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Expression in the mutant middle ear ossicle and inner ear developing joints was similar to control.
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| TS22: connective tissue |
Present |
Regionally restricted |
3F
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Expression in the mutant middle ear ossicle developing annular ligament was similar to control.
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Specimen
3I:
embryonic day 18.5
(more )
Specimen
3I:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: skeletal joint |
Present |
Regionally restricted |
3I
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Expression was detected in the incudostapedial joint.
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| TS26: ligament |
Present |
Regionally restricted |
3I
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Expression was detected in the annular ligament.
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Specimen
3M:
(close )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Cxcl12tm1Spo/Cxcl12tm1Spo
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: skeletal joint |
Present |
Regionally restricted |
3M
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Expression in the mutant incudostapedial joint was similar to control.
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| TS26: ligament |
Present |
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3M
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Expression in the mutant annular ligament was similar to control.
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Analysis Tools
